Isatuximab Treatment in Refractory T-Acute Lymphoblastic Leukemia The difficulty of making an accurate prognosis of acute T- cell lymphoblastic leukemia (T- ALL) and T- cell lymphoblastic lymphoma (T- LBL) in seniors and patients with relapsed illness has always been an issue in the medical field. Since there is no specified standard
Ocular Melanoma and Treatment with Metformin
Ocular Melanoma and Treatment with Metformin Metformin Activity Metformin is one of the most common medications for patients with type 2 diabetes mellitus. It is an antihyperglycemic agent that activates the adenosine monophosphate-activated kinase (AMPK). Through this, a person’s cellular ATP levels are restored. The activation of AMPK by metformin suggests that
Gastric Neuroendocrine Neoplasms
Gastric Neuroendocrine Neoplasms Overview Gastric neuroendocrine neoplasms are rare lesions found in the stomach. They grow slowly and are often divided into four types based on their clinical characteristics. Type I lesions are found in the stomach and are linked with autoimmune chronic atrophic gastritis. Type II lesions are often caused by
Lung Cancer with Brain Metastasis After Late-Onset Bipolar Disorder: A Case Report
Lung Cancer with Brain Metastasis After Late-Onset Bipolar Disorder: A Case Report Background Bipolar disorder is a multifactorial illness with uncertain etiology and geriatric new-onset manic episodes are highly associated with secondary organic causes. The presented case demonstrates the importance of excluding secondary causes during the entire disease course. Overview Bipolar disorder is a
How to Sleep When You Are Not Tired
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. How to Sleep When You Are Not Tired There are times when you know that you should get some sleep, but you just don’t feel tired enough actually to fall
Anlotinib with Camrelizumab in Lung Cancer Treatment
Anlotinib with Camrelizumab in Lung Cancer Treatment Background Checkpoint inhibitors (CPIs) and anti-angiogenic agents are emerging as potential novel treatment choices for advanced cancers including metastatic non-small-cell lung cancer (NSCLC). However, the combination of these two standard therapies has not been investigated in third-line or further-line treatment of patients with advanced NSCLC.
Sebaceous Carcinoma Treatment Outcomes: A Multicenter Study
Sebaceous Carcinoma Treatment Outcomes Sebaceous carcinoma (SC) is a rare tumor found in the sebaceous glands. The sebaceous gland is the gland that lubricates our skin. Although it can develop anywhere on the body, sebaceous carcinomas are often found on eyelids. It’s responsible for 0.7% of all cutaneous malignancies. From 2000
5 Health Trends to Follow in 2022
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. 5 Health Trends to Follow in 2022 With each passing year, we observe an increasing health awareness among people of all ages. While the prevalence of a health-conscious mindset is
Diffuse-Type Tenosynovial Giant Cell Tumors: Treatments and Progression
Diffuse-Type Tenosynovial Giant Cell Tumors: Treatments and Progression Tenosynovial giant cell tumors (TGCT) - An Introduction Tenosynovial giant cell tumors (TGCT) are rare, locally invasive lesions of synovial origin that involve joints, tendon sheaths, and bursae. TGCT may be intra- or extra-articular and is classified by growth pattern and clinical presentation as
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report Overview A male patient, 52 years of age, underwent pneumonectomy of the left lung. He was previously diagnosed with primary spindle cell carcinoma (pT4aN1M0, stage III B) with programmed death-ligand 1 expression (tumor proportion score ≥95%) and without epidermal growth factor
