Is Isotretinoin Overregulated or Underused Balancing Teratogenic Risk, Safety Evidence, and Access Review Abstract Background: Oral isotretinoin is strongly recommended for severe acne, acne causing scarring or major psychosocial burden, and disease that has not responded to standard topical or oral therapy. It is also a
Dermatology
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer Review Abstract Background Evaluation of an identified suspicious skin lesion is fundamentally distinct from routine skin cancer screening. The U.S. Preventive Services Task Force (USPSTF) concludes that evidence is insufficient to
Melanoma Screening in the AI Era: Why Dermatologists Remain the Clinical Standard and AI Should Stay an Adjunct
Melanoma Screening in the AI Era: Why Dermatologists Remain the Clinical Standard and AI Should Stay an Adjunct Review Abstract Purpose: Melanoma remains one of the most aggressive forms of skin cancer, accounting for a disproportionate number of skin cancer related deaths despite representing a relatively small
Topical vs Systemic Therapy in Psoriasis: Escalating Wisely in the Biologic Era
Topical vs Systemic Therapy in Psoriasis: Escalating Wisely in the Biologic Era Review Abstract Purpose: This review examines how clinicians should decide among optimized topical therapy, phototherapy, oral systemic treatment, and biologic therapy in plaque psoriasis. Methodology: Review of recent clinical guidelines, FDA prescribing information,
Nail Disorders as Clues to Systemic Disease: Evidence, Limitations, and Diagnostic Value in Clinical Practice
Nail Disorders as Clues to Systemic Disease: Evidence, Limitations, and Diagnostic Value in Clinical Practice Review Abstract The physical examination remains a cornerstone of clinical medicine, yet certain components are frequently overlooked despite their diagnostic value. Among these, examination of the nail unit represents a
The Microbiome in Dermatology: Hype, Hope, or Future Standard of Care?
The Microbiome in Dermatology: Hype, Hope, or Future Standard of Care? Review Abstract The human skin microbiome has emerged as a critical factor in dermatological health and disease. This paper examines the current state of microbiome research in dermatology, evaluating whether the field represents scientific
Skin of Color Dermatology: Why Current Medical Guidelines Are Leaving Patients Behind
Skin of Color Dermatology: Why Current Medical Guidelines Are Leaving Patients Behind Review Key Takeaways Contemporary dermatology practice continues to demonstrate significant limitations in the diagnosis and management of conditions in patients with darker skin tones, contributing to measurable disparities in clinical outcomes. As individuals
Cosmeceuticals vs Prescription Therapy: Where Does Science End and Marketing Begin?
Cosmeceuticals vs Prescription Therapy: Where Does Science End and Marketing Begin? Review Abstract The distinction between cosmeceuticals and prescription dermatologic therapies has become progressively less defined, creating a complex therapeutic landscape for clinicians and patients. Cosmeceuticals are commonly described as topical products that occupy an
The Explosion of At-Home Dermatology Significant Threat or Opportunity?
The Explosion of At-Home Dermatology Significant Threat or Opportunity Abstract The rapid expansion of at home dermatology devices has generated significant interest within both consumer markets and the medical community. Over the past decade, advances in miniaturized technology, digital connectivity, and consumer health awareness have driven the
New Treatments for Atopic Dermatitis in 2026: Why More Options Might Be Making Your Choice Harder
New Treatments for Atopic Dermatitis in 2026 Why More Options Might Be Making Your Choice Harder Key Takeaways The treatment landscape for atopic dermatitis has changed profoundly over the past several years, moving from a limited set of broadly acting immunosuppressive therapies to an increasingly sophisticated range
