Knee Osteoarthritis Improvements Using Telehealth Exercise Programs Overview This study aimed to investigate the factors that mediate the impact of two 6-month telehealth-delivered exercise programs, with and without a weight-loss diet, on pain and function improvements in individuals with knee osteoarthritis (OA). The secondary analysis involved 345 participants from a 3-arm randomized
Author: Nancy Ogbonna
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients Overview In this retrospective cohort study utilizing IQVIA PharMetrics Plus claims data, the effectiveness of mepolizumab, a humanized anti-interleukin 5 monoclonal antibody, was explored in a real-world setting for U.S. patients with severe asthma and comorbid chronic rhinosinusitis (CRS) with or without sinus
Patellofemoral Arthroplasty Designs and Osteoarthritis Progression
Patellofemoral Arthroplasty Designs and Osteoarthritis Progression Overview This study aimed to evaluate clinical and functional outcomes, complication rates, implant survivorship, and the progression of tibiofemoral osteoarthritis (OA) in patients with isolated patellofemoral OA undergoing new inlay or onlay patellofemoral arthroplasty (PFA). The research also sought to compare different implant types and models
Cognitive Behavioral Therapy: Telehealth Effectiveness For Chronic Mental Disorders
Cognitive Behavioral Therapy: Telehealth Effectiveness For Chronic Mental Disorders Overview Amidst the pandemic, the adoption of remote treatments, specifically telephone-delivered cognitive behavioral therapy (T-CBT), has witnessed a notable increase. This meta-analysis seeks to fill a gap in existing literature by evaluating the effectiveness of T-CBT in chronic and/or mental illnesses, comparing it
Gout in Patients With Inflammatory Bowel Disease
Gout in Patients with Inflammatory Bowel Disease Overview Arthritis is a well-established extra-intestinal manifestation of inflammatory bowel disease (IBD). Recent studies have indicated disruptions in uric acid metabolism among individuals with IBD. This investigation aimed to explore the link between IBD and gout using a comprehensive multi-center database (Explorys Inc.) comprising data
Alcohol Consumption And The Long-Term Risk Of Mortality
Alcohol Consumption And The Long-Term Risk Of Mortality Overview This study aims to update a previous systematic review by conducting a comprehensive analysis of meta-analyses published from January 1, 2017, to March 8, 2021, to quantify sex-specific dose–response risk relationships between chronic alcohol consumption and disease occurrence and mortality. The systematic search
Obesity Classification And The Risk Of Gallstones
Obesity Classification And The Risk Of Gallstones Overview This population-based cross-sectional study aimed to determine the most effective predictor of gallstone disease (GSD) among various anthropometric indicators of obesity. The research, conducted in Taiwan from 2014 to 2017, included 2263 participants who underwent physical examinations, provided blood samples, and completed detailed questionnaires
Antidiabetic Medications And Dementia Risk
Antidiabetic Medications And Dementia Risk Overview This umbrella review and meta-analysis aimed to assess the impact of diabetes on dementia risk and investigate the potential mitigating effects of various antidiabetic treatments. The study conducted a systematic review on diabetes and its treatment, along with a meta-analysis specifically focusing on treatment outcomes. A comprehensive
Cannabis Medicinal Products For Fibromyalgia Pain
Cannabis Medicinal Products For Fibromyalgia Pain Overview This study aimed to assess the impact of cannabis-based medicinal products (CBMPs) on individuals with fibromyalgia, considering changes in health-related quality of life and adverse events. The research, conducted on 306 patients identified from the UK Medical Cannabis Registry, revealed significant improvements in overall health-related
Prostate Cancer Detection Using Urine Glycoproteins
Prostate Cancer Detection Using Urine Glycoproteins Overview In a recent study, researchers investigated the potential of using pre-digital rectal examination (DRE) urine specimens to detect aggressive prostate cancer (AG-PCa) by comparing glycoproteins found in pre- and post-DRE urine samples. The study involved 154 pre-DRE urine specimens from individuals with no cancer at
