Neuromodulation for Depression and Chronic Pain: Beyond Deep Brain Stimulation Review Abstract Neuromodulation therapies have become increasingly important in the management of treatment resistant depression and chronic pain, two conditions that continue to impose substantial personal, societal, and economic burdens worldwide. Despite significant advances in pharmacologic and psychotherapeutic interventions,
Author: Nancy Ogbonna
Obesity, Metabolic Syndrome, and ‘Difficult-to-Treat’ Psoriatic Arthritis: Is Inflammation Only Half the Story?
Obesity, Metabolic Syndrome, and ‘Difficult-to-Treat’ Psoriatic Arthritis Is Inflammation Only Half the Story Review Abstract Psoriatic arthritis (PsA) is a chronic, immune mediated inflammatory musculoskeletal disease that affects a substantial proportion of individuals with psoriasis. Characterized by peripheral arthritis, enthesitis, dactylitis, axial involvement, and progressive joint damage, PsA is associated
Plasma Biomarkers for Neurodegenerative Disease: What Clinicians Need to Know in 2026
Plasma Biomarkers for Neurodegenerative Disease What Clinicians Need to Know in 2026 Review Key Takeaways Plasma biomarkers are rapidly transforming the diagnosis and management of Alzheimer’s disease and related dementias, representing one of the most notable advances in neurodegenerative medicine in recent decades. Historically, the definitive assessment of Alzheimer’s pathology has
Revolutionizing Diabetes Monitoring: Beyond A1C to Continuous Metabolic Profiling
Revolutionizing Diabetes Monitoring Beyond A1C to Continuous Metabolic Profiling Review Abstract Diabetes mellitus remains one of the most prevalent and challenging chronic diseases worldwide, affecting hundreds of millions of individuals and contributing significantly to cardiovascular disease, kidney failure, blindness, neuropathy, and premature mortality. Effective diabetes management
How to Define Analgesia and Implement Safe Opioid Therapy Protocols in Family Medicine
How to Define Analgesia and Implement Safe Opioid Therapy Protocols in Family Medicine Review Key Takeaways Family physicians occupy a central position in the management of acute and chronic pain, making safe opioid prescribing a critical component of primary care practice. As opioid related morbidity and mortality
The New Face of Delirium: Sedative Stewardship, Antipsychotic Backlash, and Non-Pharmacologic Protocols
The New Face of Delirium Sedative Stewardship, Antipsychotic Backlash, and Non-Pharmacologic Protocols Review Abstract Purpose:This review examines the evolving landscape of delirium management in contemporary clinical practice, with particular emphasis on three interconnected areas that are reshaping patient care: the implementation of sedative stewardship programs, increasing concerns
Cerebral Small Vessel Disease: The Hidden Driver of Cognitive Decline
Cerebral Small Vessel Disease: The Hidden Driver of Cognitive Decline Review Abstract Cerebral small vessel disease (CSVD) represents one of the most common yet underrecognized causes of cognitive impairment and functional decline worldwide. The condition affects the brain’s smallest blood vessels and leads to a
Emergency Department Boarding: Patient Safety Crisis or Hospital Failure?
Emergency Department Boarding: Patient Safety Crisis or Hospital Failure? Review Abstract Emergency department (ED) boarding represents one of the most pressing challenges facing modern healthcare systems. This phenomenon occurs when patients who require hospital admission remain in emergency departments for extended periods because of a lack
Fluorescence-Guided Surgery: From Indocyanine Green to Tumor-Specific Fluorophores in 2026
Fluorescence-Guided Surgery: From Indocyanine Green to Tumor-Specific Fluorophores in 2026 Review Key Takeaways Fluorescence-guided surgery (FGS) is reshaping oncologic surgery by enabling real-time molecular visualization of tumors and critical anatomical structures. The field has evolved from non-specific fluorescent dyes toward highly targeted fluorophores capable of identifying malignant
Insomnia in Primary Care: Implementation of CBT
Insomnia in Primary Care: Implementation of CBT Review Abstract Insomnia is one of the most prevalent sleep disorders encountered in primary care and affects approximately 10–15% of adults worldwide. Chronic insomnia is associated with substantial impairments in daytime functioning, increased healthcare utilization, psychiatric and medical comorbidity, and reduced
