CIDP Overdiagnosis and IVIG Stewardship: Are We Treating the Right Patients for the Right Duration? Review Abstract Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a highly treatable immune-mediated neuropathy. However, establishing the diagnosis requires a careful integration of the clinical phenotype, electrodiagnostic findings, appropriate supportive evidence,
Neurology
Quantitative Neuromuscular Monitoring: Why Are We Still Guessing at Recovery?
Quantitative Neuromuscular Monitoring Why Are We Still Guessing at Recovery Review Abstract Purpose: This review critically evaluates the scientific rationale, current evidence, professional guideline recommendations, and practical implementation of quantitative neuromuscular monitoring during recovery from neuromuscular blockade, with particular emphasis on patients receiving nondepolarizing neuromuscular blocking
Functional Neurological Disorder: From Diagnosis of Exclusion to Rule-In Neurology
Functional Neurological Disorder: From Diagnosis of Exclusion to Rule-In Neurology Review Positive Signs, Diagnostic Safety, and Practical Treatment Pathways for Clinicians Abstract Purpose: This article reviews functional neurological disorder (FND) as a modern rule-in diagnosis, emphasizing positive clinical signs, diagnostic safety, clinician communication, functional seizures,
Normal Pressure Hydrocephalus: The Reversible Dementia We Still Miss
Normal Pressure Hydrocephalus: The Reversible Dementia We Still Miss Review Abstract Purpose: This review examines normal pressure hydrocephalus (NPH), emphasizing timely clinical recognition, evidence-based diagnostic strategies, patient selection for surgical intervention, anticipated outcomes after cerebrospinal fluid shunting, medication-related confounders, and procedural safety considerations. As one
Autism Spectrum Disorder and Early Detection: The Emerging Role of AI-Assisted Diagnostic Aids
Autism Spectrum Disorder and Early Detection: The Emerging Role of AI-Assisted Diagnostic Aids Review Abstract Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by persistent differences in social communication and social interaction, accompanied by restricted, repetitive patterns of behavior, interests, or activities. The condition
Posterior Cortical Atrophy, Primary Progressive Aphasia, and the Non-Amnestic Alzheimer’s Patient
Posterior Cortical Atrophy, Primary Progressive Aphasia, and the Non-Amnestic Alzheimer's Patient Review Abstract Alzheimer's disease is often marked by progressive episodic memory loss, but not all patients start with an amnestic syndrome. Some patients may initially present with issues in visual-spatial skills, language, executive function,
Frontotemporal Dementia After the Bruce Willis Effect: What Neurologists Should Revisit
Frontotemporal Dementia After the Bruce Willis Effect What Neurologists Should Revisit Review Abstract The public disclosure of a frontotemporal dementia diagnosis by Bruce Willis brought unprecedented public attention to a neurodegenerative disorder that has historically remained underrecognized outside specialized neurology and memory clinics. While increased awareness has
Lecanemab in Real-World Practice: What Early Alzheimer’s Patients Are Actually Experiencing
Lecanemab in Real-World Practice: What Early Alzheimer’s Patients Are Actually Experiencing Review Abstract Lecanemab represents a major milestone in the treatment of Alzheimer’s disease as the first anti amyloid monoclonal antibody to receive traditional approval from the United States Food and Drug Administration for patients with early
Neuromodulation for Depression and Chronic Pain: Beyond Deep Brain Stimulation
Neuromodulation for Depression and Chronic Pain: Beyond Deep Brain Stimulation Review Abstract Neuromodulation therapies have become increasingly important in the management of treatment resistant depression and chronic pain, two conditions that continue to impose substantial personal, societal, and economic burdens worldwide. Despite significant advances in pharmacologic and psychotherapeutic interventions,
Plasma Biomarkers for Neurodegenerative Disease: What Clinicians Need to Know in 2026
Plasma Biomarkers for Neurodegenerative Disease What Clinicians Need to Know in 2026 Review Key Takeaways Plasma biomarkers are rapidly transforming the diagnosis and management of Alzheimer’s disease and related dementias, representing one of the most notable advances in neurodegenerative medicine in recent decades. Historically, the definitive assessment of Alzheimer’s pathology has
