Rethinking Routine Preoperative Benzodiazepines: Better Brain Health or Unnecessary Anxiety?

Evidence-based clinical review Rethinking Routine Preoperative Benzodiazepines Better Brain Health or Unnecessary Anxiety Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background Routine benzodiazepine premedication, particularly midazolam, is being removed from many perioperative

The Psychiatry of Long COVID: Brain Fog, Depression, and Beyond

Evidence-based clinical review The Psychiatry of Long COVID Brain Fog, Depression, and Beyond Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background Long COVID represents an infection-associated chronic condition that can profoundly

Pharmacologic Management of Major Depressive Disorder in Primary Care: An Algorithm for Partial Response, Switching, and Augmentation

Evidence-based clinical review Pharmacologic Management of Major Depressive Disorder in Primary Care An Algorithm for Partial Response, Switching, and Augmentation  Estimated reading time: 15 minutes Abstract Background: An inadequate response to an initial antidepressant is incredibly common

Environmental and Lifestyle Hematology: How Air Pollution and Chronic Stress Influence Hematopoiesis, Inflammation, and Vascular Risk

Environmental and Lifestyle Hematology: The Influence of Air Pollution and Chronic Stress on Hematopoiesis, Inflammation, and Vascular Risk Review Abstract Purpose: This review examines how fine particulate air pollution and chronic psychosocial stress may influence hematopoiesis, inflammatory leukocyte production, coagulation biology, clonal hematopoiesis, and cardiovascular risk.

Autism Spectrum Disorder and Early Detection: The Emerging Role of AI-Assisted Diagnostic Aids

Autism Spectrum Disorder and Early Detection: The Emerging Role of AI-Assisted Diagnostic Aids Review Abstract Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by persistent differences in social communication and social interaction, accompanied by restricted, repetitive patterns of behavior, interests, or activities. The condition

Neuromodulation for Depression and Chronic Pain: Beyond Deep Brain Stimulation

Neuromodulation for Depression and Chronic Pain: Beyond Deep Brain Stimulation Review Abstract Neuromodulation therapies have become increasingly important in the management of treatment resistant depression and chronic pain, two conditions that continue to impose substantial personal, societal, and economic burdens worldwide. Despite significant advances in pharmacologic and psychotherapeutic interventions,

Plasma Biomarkers for Neurodegenerative Disease: What Clinicians Need to Know in 2026

Plasma Biomarkers for Neurodegenerative Disease What Clinicians Need to Know in 2026 Review Key Takeaways Plasma biomarkers are rapidly transforming the diagnosis and management of Alzheimer’s disease and related dementias, representing one of the most notable advances in neurodegenerative medicine in recent decades. Historically, the definitive assessment of Alzheimer’s pathology has

The New Face of Delirium: Sedative Stewardship, Antipsychotic Backlash, and Non-Pharmacologic Protocols

The New Face of Delirium Sedative Stewardship, Antipsychotic Backlash, and Non-Pharmacologic Protocols Review Abstract Purpose:This review examines the evolving landscape of delirium management in contemporary clinical practice, with particular emphasis on three interconnected areas that are reshaping patient care: the implementation of sedative stewardship programs, increasing concerns

Insomnia in Primary Care: Implementation of CBT

Insomnia in Primary Care: Implementation of CBT Review Abstract Insomnia is one of the most prevalent sleep disorders encountered in primary care and affects approximately 10–15% of adults worldwide. Chronic insomnia is associated with substantial impairments in daytime functioning, increased healthcare utilization, psychiatric and medical comorbidity, and reduced

Pediatric Mental Health Crisis: Navigating the Surge in Anxiety and Depression

Pediatric Mental Health Crisis Navigating the Surge in Anxiety and Depression Review Abstract The current state of pediatric mental health has emerged as one of the most urgent and complex challenges confronting healthcare systems worldwide. Anxiety and depressive disorders among children and adolescents have increased substantially over the past

Rethinking Routine Preoperative Benzodiazepines: Better Brain Health or Unnecessary Anxiety?