Lecanemab in Real-World Practice: What Early Alzheimer’s Patients Are Actually Experiencing Review Abstract Lecanemab represents a major milestone in the treatment of Alzheimer’s disease as the first anti amyloid monoclonal antibody to receive traditional approval from the United States Food and Drug Administration for patients with early
Tag: cognitive decline
Plasma Biomarkers for Neurodegenerative Disease: What Clinicians Need to Know in 2026
Plasma Biomarkers for Neurodegenerative Disease What Clinicians Need to Know in 2026 Review Key Takeaways Plasma biomarkers are rapidly transforming the diagnosis and management of Alzheimer’s disease and related dementias, representing one of the most notable advances in neurodegenerative medicine in recent decades. Historically, the definitive assessment of Alzheimer’s pathology has
Cerebral Small Vessel Disease: The Hidden Driver of Cognitive Decline
Cerebral Small Vessel Disease: The Hidden Driver of Cognitive Decline Review Abstract Cerebral small vessel disease (CSVD) represents one of the most common yet underrecognized causes of cognitive impairment and functional decline worldwide. The condition affects the brain’s smallest blood vessels and leads to a
Hidden Cognitive Decline Symptoms: What Every Internist Must Know Today
Hidden Cognitive Decline Symptoms: What Every Internist Must Know Today Check out our extensive video library (see channel for our latest videos) Introduction Cognitive decline symptoms often go undetected in clinical settings, despite affecting approximately 16.6% of Americans aged 65 and older who experience
Smart Devices Detect Early Cognitive Decline
Hearing Loss And Functional Decline
Hearing Loss And Functional Decline Overview Hearing loss has been recognized as one of the major modifiable risk factors for cognitive decline and dementia. However, studies exploring this connection have yielded mixed results. This study aimed to assess the long-term relationship between self-reported hearing loss and cognitive/functional abilities in 695 cognitively
Cataract Surgery Impact On Cognitive Test Scores
Cataract Surgery Impact On Cognitive Test Scores Overview This prospective observational study aimed to assess the impact of cataract surgery on mild cognitive impairment (MCI) and dementia in individuals aged 75 years and older. Conducted between 2019 and 2021, the study involved 88 eligible patients who underwent cataract surgery. Cognitive function was
Alzheimer’s Patients and Low Tau Burden Outcomes
Alzheimer's Patients and Low Tau Burden Outcomes Overview The study focuses on individuals within the Alzheimer's Disease (AD) pathway exhibiting abnormal amyloid-beta (Aβ) and tau deposition. Specifically, it investigates a subgroup characterized by low tau levels (A+T−) and compares them to their counterparts with higher tau levels (A+T+). The research involves 397 individuals
White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients
White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients Overview In this study, the objective was to evaluate white matter microstructural changes in older breast cancer survivors 5-15 years post-chemotherapy treatment. The participants included breast cancer survivors aged 65 or older who underwent chemotherapy (C+) and those who did not (C-), along
Multimorbidity In Patients With Cognitive Impairment And Dementia
Multimorbidity In Patients With Cognitive Impairment And Dementia Overview The study aimed to investigate the burden and clusters of multimorbidity in relation to mild cognitive impairment (MCI), dementia, and Alzheimer's disease (AD)-related plasma biomarkers among older adults. A population-based sample of 5432 participants aged 60 years and above was included, with a
