Small Fiber Neuropathy: When EMG Is Normal but the Patient Is Not

Evidence-based clinical review Small Fiber Neuropathy: When EMG Is Normal but the Patient Is Not A practical framework for recognizing the phenotype, confirming small-fiber dysfunction, finding treatable causes, and avoiding diagnostic overreach Abstract Background: Small fiber neuropathy

Triple Therapy for COPD: Who Benefits, Who Is at Risk for Pneumonia, and Who May Be Overtreated?

Evidence-based clinical review Triple Therapy for COPD: Who Benefits, Who Is at Risk for Pneumonia, and Who May Be Overtreated? A phenotype- and exacerbation-based approach to adding, continuing, or withdrawing inhaled corticosteroids Estimated reading time: 16 minutes

Ultrasound-Guided Central Venous Access: Is Landmark-Only Placement Now Outdated?

Evidence-based clinical review Ultrasound-Guided Central Venous Access: Is Landmark-Only Placement Now Outdated? For routine central venous catheterization, real-time ultrasound should be the default when trained operators and functioning equipment are available. Landmark-only access still has a limited contingency role. Estimated reading time:

C. difficile in 2026: Are We Finally Preventing Recurrence More Effectively?

Evidence-based clinical review C. difficile in 2026: Are We Finally Preventing Recurrence More Effectively? Fidaxomicin, microbiota restoration, and risk-stratified care have changed the recurrence conversation, but access and evidence gaps still matter. Estimated reading time: 16 minutes

Early Pregnancy Bleeding: A Risk-Based Playbook for Pregnancy of Unknown Location and Ectopic Pregnancy

Evidence-based clinical review Early Pregnancy Bleeding: A Risk-Based Playbook for Pregnancy of Unknown Location and Ectopic Pregnancy How to integrate symptoms, transvaginal ultrasound, hCG trajectories, pregnancy goals, and follow-up capacity without overcalling a single threshold Estimated reading time: 17 minutes

CGRP-Targeted Migraine Prevention as a First-Line Option: A Family Medicine Prescribing Framework

Evidence-based clinical review CGRP-Targeted Migraine Prevention as a First-Line Option: A Family Medicine Prescribing Framework Reconciling AHS and ACP guidance, selecting oral, injectable, and infusion therapies, and monitoring the updated 2026 safety warnings Estimated reading time: 17 minutes

Caregiver Burden as a Hidden Vital Sign in Dementia Care: Why Routine Measurement Belongs in Geriatric Practice

Evidence-based clinical review Caregiver Burden as a Hidden Vital Sign in Dementia Care: Why Routine Measurement Belongs in Geriatric Practice A brief, repeated measure can reveal risks that patient-only assessment misses, but screening should be linked to a defined clinical response. Estimated

Anesthesia for Robotic Pelvic Surgery: The Hidden Physiology of Steep Trendelenburg and Pneumoperitoneum

Evidence-based clinical review Anesthesia for Robotic Pelvic Surgery: The Hidden Physiology of Steep Trendelenburg and Pneumoperitoneum Why apparently reassuring numbers can conceal cardiopulmonary, cerebral, ocular, airway, and renal stress Estimated reading time: 17 minutes Abstract

Intratumoral Immunotherapy and In-Situ Vaccination: Local Shots, Systemic Responses?

Evidence-based clinical review Intratumoral Immunotherapy and In-Situ Vaccination: Local Shots, Systemic Responses? What clinicians should know about tumor-directed immune therapy, distant lesion responses, and the limits of current evidence Estimated reading time: 20 minutes Abstract

Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics?

Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics? Review Abstract Background Management of adult sepsis requires prompt decision-making amid uncertainty about infection, organ dysfunction, hemodynamic status, and treatment responsiveness. Although standardized care pathways may reduce harmful delays, indiscriminate

Small Fiber Neuropathy: When EMG Is Normal but the Patient Is Not