Is Isotretinoin Overregulated or Underused Balancing Teratogenic Risk, Safety Evidence, and Access Review Abstract Background: Oral isotretinoin is strongly recommended for severe acne, acne causing scarring or major psychosocial burden, and disease that has not responded to standard topical or oral therapy. It is also a
OBGYN
Recurrent Pregnancy Loss: Evidence-Based Evaluation, Treatment, and Legacy Practices
Revisiting Hormone Replacement Therapy: Are the Risks Still Overstated?
Revisiting Hormone Replacement Therapy: Are the Risks Still Overstated? Review Abstract Purpose: This paper reviews whether the risks of menopausal hormone therapy have been overstated in contemporary practice and how clinicians can apply current evidence without minimizing established safety concerns. Methodology: Review of current society
Permanent Contraception: Salpingectomy vs Tubal Ligation. What’s Your Default Now?
Permanent Contraception: Salpingectomy Versus Tubal Ligation - Current Default Approaches Review Abstract Purpose: This review evaluates complete bilateral salpingectomy and traditional tubal ligation, tubal occlusion, or partial salpingectomy as surgical options for permanent contraception. It compares contraceptive effectiveness, perioperative safety, operative feasibility, ovarian function, cancer-risk
The Cervical Screening Shake-Up: Primary HPV Testing, Genotyping, and Real-World Confusion
The Cervical Screening Shake-Up: Primary HPV Testing, Genotyping, and Real-World Confusion Review Abstract The transition from cytology-centered cervical cancer screening to primary high-risk human papillomavirus testing represents one of the most important changes in preventive gynecologic care. Primary HPV testing is more sensitive than cytology
Osteoporosis Treatment Sequencing: Where Do the Anabolics Fit In?
Osteoporosis Treatment Sequencing Where Do the Anabolics Fit In Review Abstract Osteoporosis management has undergone a remarkable transformation in recent years, moving away from a uniform antiresorptive-first treatment paradigm toward a more individualized, risk-based approach that prioritizes fracture prevention according to the patient’s absolute risk profile. This evolution
Abnormal Uterine Bleeding: When to Stop ‘Try Another Pill’ and Go Procedural
Abnormal Uterine Bleeding: When to Stop 'Try Another Pill' and Go Procedural Review Abstract Abnormal uterine bleeding affects up to 30% of reproductive-age women and represents a major healthcare burden. While hormonal contraceptives remain first-line therapy, practitioners often cycle through multiple formulations without clear endpoints.
Biologics in Pregnancy and Lactation: How Aggressive Can We Safely Be?
Biologics in Pregnancy and Lactation: How Aggressive Can We Safely Be? Review Abstract Biologic therapies have transformed the management of chronic inflammatory and autoimmune diseases by targeting specific components of the immune system. Their use has led to significant improvements in disease control, quality of life, and
Endometriosis: Novel Medical Therapies Beyond GnRH Agonists
Endometriosis Novel Medical Therapies Beyond GnRH Agonists Abstract Endometriosis affects an estimated 10 to 15 percent of women of reproductive age and remains one of the most complex and therapeutically challenging conditions in gynecology. Characterized by the presence of endometrial-like tissue outside the uterine
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns?
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns? Abstract This paper reviews the current body of evidence regarding the safety and effectiveness of messenger RNA COVID-19 vaccines during pregnancy and explores the broader implications for emerging mRNA vaccine platforms intended for use in pregnant populations.
