The Cervical Screening Shake-Up: Primary HPV Testing, Genotyping, and Real-World Confusion Review Abstract The transition from cytology-centered cervical cancer screening to primary high-risk human papillomavirus testing represents one of the most important changes in preventive gynecologic care. Primary HPV testing is more sensitive than cytology
OBGYN
Osteoporosis Treatment Sequencing: Where Do the Anabolics Fit In?
Osteoporosis Treatment Sequencing Where Do the Anabolics Fit In Review Abstract Osteoporosis management has undergone a remarkable transformation in recent years, moving away from a uniform antiresorptive-first treatment paradigm toward a more individualized, risk-based approach that prioritizes fracture prevention according to the patient’s absolute risk profile. This evolution
Abnormal Uterine Bleeding: When to Stop ‘Try Another Pill’ and Go Procedural
Abnormal Uterine Bleeding: When to Stop 'Try Another Pill' and Go Procedural Review Abstract Abnormal uterine bleeding affects up to 30% of reproductive-age women and represents a major healthcare burden. While hormonal contraceptives remain first-line therapy, practitioners often cycle through multiple formulations without clear endpoints.
Biologics in Pregnancy and Lactation: How Aggressive Can We Safely Be?
Biologics in Pregnancy and Lactation: How Aggressive Can We Safely Be? Review Abstract Biologic therapies have transformed the management of chronic inflammatory and autoimmune diseases by targeting specific components of the immune system. Their use has led to significant improvements in disease control, quality of life, and
Endometriosis: Novel Medical Therapies Beyond GnRH Agonists
Endometriosis Novel Medical Therapies Beyond GnRH Agonists Abstract Endometriosis affects an estimated 10 to 15 percent of women of reproductive age and remains one of the most complex and therapeutically challenging conditions in gynecology. Characterized by the presence of endometrial-like tissue outside the uterine
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns?
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns? Abstract This paper reviews the current body of evidence regarding the safety and effectiveness of messenger RNA COVID-19 vaccines during pregnancy and explores the broader implications for emerging mRNA vaccine platforms intended for use in pregnant populations.
Noninvasive Prenatal Testing (NIPT): What’s Next After Aneuploidy?
Noninvasive Prenatal Testing (NIPT) What’s Next After Aneuploidy Abstract Noninvasive prenatal testing has fundamentally reshaped prenatal screening by enabling highly accurate detection of fetal chromosomal abnormalities through analysis of cell free fetal DNA circulating in maternal blood. Since its clinical introduction, NIPT has been widely
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility: Mechanisms, Evidence, and Clinical Implications Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are well established for the treatment of type 2 diabetes mellitus and obesity. Increasingly, reports suggest a possible association between GLP-1 RA use and
Preeclampsia Prediction and Prevention: Are We Entering a New Era?
Preeclampsia Prediction and Prevention Are We Entering a New Era Abstract Preeclampsia remains a major contributor to maternal and perinatal morbidity and mortality worldwide, affecting an estimated 2 to 8 percent of pregnancies. Despite advances in obstetric care, the condition continues to pose significant challenges
Uterine Transplant Success Rates: Breakthrough Data from 2025 Clinical Trials
Uterine Transplant Success Rates Breakthrough Data from 2025 Clinical Trials Introduction Uterine transplantation has emerged as a transformative therapeutic option for women with uterine factor infertility, a condition that affects approximately five percent of women of reproductive age worldwide. Uterine factor infertility is defined
