Caregiver Burden as a Hidden Vital Sign in Dementia Care: Why Routine Measurement Belongs in Geriatric Practice

Evidence-based clinical review Caregiver Burden as a Hidden Vital Sign in Dementia Care: Why Routine Measurement Belongs in Geriatric Practice A brief, repeated measure can reveal risks that patient-only assessment misses, but screening should be linked to a defined clinical response. Estimated

Anesthesia for Robotic Pelvic Surgery: The Hidden Physiology of Steep Trendelenburg and Pneumoperitoneum

Evidence-based clinical review Anesthesia for Robotic Pelvic Surgery: The Hidden Physiology of Steep Trendelenburg and Pneumoperitoneum Why apparently reassuring numbers can conceal cardiopulmonary, cerebral, ocular, airway, and renal stress Estimated reading time: 17 minutes Abstract

Intratumoral Immunotherapy and In-Situ Vaccination: Local Shots, Systemic Responses?

Evidence-based clinical review Intratumoral Immunotherapy and In-Situ Vaccination: Local Shots, Systemic Responses? What clinicians should know about tumor-directed immune therapy, distant lesion responses, and the limits of current evidence Estimated reading time: 20 minutes Abstract

Prehospital Blood Products: Determining Which EMS Units Should Carry Them

Evidence-based clinical review Prehospital Blood Products Determining Which EMS Units Should Carry Them Clinical Notes No, not every EMS unit should carry blood. The most defensible goal is reliable regional access to early transfusion. This is best achieved through selected assets that can maintain

Pharmacologic Management of Major Depressive Disorder in Primary Care: An Algorithm for Partial Response, Switching, and Augmentation

Evidence-based clinical review Pharmacologic Management of Major Depressive Disorder in Primary Care An Algorithm for Partial Response, Switching, and Augmentation  Estimated reading time: 15 minutes Abstract Background: An inadequate response to an initial antidepressant is incredibly common

Is Isotretinoin Overregulated or Underused? Balancing Teratogenic Risk, Safety Evidence, and Access

Is Isotretinoin Overregulated or Underused Balancing Teratogenic Risk, Safety Evidence, and Access Review Abstract Background: Oral isotretinoin is strongly recommended for severe acne, acne causing scarring or major psychosocial burden, and disease that has not responded to standard topical or oral therapy. It is also a

Recurrent Pregnancy Loss: Evidence-Based Evaluation, Treatment, and Legacy Practices

Evidence-based clinical review Recurrent Pregnancy Loss Evidence-Based Evaluation, Treatment, and Legacy Practices A 2026 guide to high-value testing, targeted treatment, and low-value add-ons Estimated reading time: 15 minutes Abstract Background: Recurrent pregnancy loss creates intense

The Neurology of Dysautonomia: POTS, Orthostatic Intolerance, and Autonomic Testing in 2026

Evidence-based clinical review The Neurology of Dysautonomia POTS, Orthostatic Intolerance, and Autonomic Testing in 2026 A Practical Neurologic Framework for Distinguishing POTS From Other Orthostatic Syndromes and Selecting Active Stand, Tilt-Table, Reflex, Sudomotor, and Small-Fiber Studies Estimated reading time: 15 minutes

Shorter Antibiotic Courses: How Short Is Too Short?

Evidence-based clinical review Shorter Antibiotic Courses: How Short Is Too Short? A syndrome-specific guide to finding the shortest effective duration in adults Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background