Statins in Absolute Terms: Mortality Benefit, Number Needed to Treat, and the Limits of Statin Therapy in Primary and Secondary Prevention Why baseline risk, endpoint choice, follow-up duration, and residual risk determine the real-world value of LDL lowering Estimated reading time: 20 minutes
Introducing the GlobalRPh Medical Terminology Learning Center, Exam Library, and six-level certificate pathway
GlobalRPh Medical Education From Medical Term Lookup to Terminology Master Introducing the GlobalRPh Medical Terminology Lookup, Learning Center, Exam Library, progress system, and six-level certificate pathway. Open the Medical Terminology Lookup Enter the Learning Center View the Exam Library Educational program, Version 2.0 | Updated
Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics?
Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics? Review Abstract Background Management of adult sepsis requires prompt decision-making amid uncertainty about infection, organ dysfunction, hemodynamic status, and treatment responsiveness. Although standardized care pathways may reduce harmful delays, indiscriminate
Antibiotic Stewardship in Pediatrics: Optimizing Diagnosis, Drug Selection, and Treatment Duration
Antibiotic Stewardship in Pediatrics: Optimizing Diagnosis, Drug Selection, and Treatment Duration Review Abstract Background Pediatric antibiotic stewardship is not synonymous with reducing antibiotic use. It is the systematic effort to prescribe antibiotics only when necessary and, when treatment is indicated, to optimize antibiotic choice, dose,
ATR and WEE1 Inhibitors After PARP Resistance: Emerging DNA Damage Response Strategies Across Solid Tumors
ATR and WEE1 Inhibitors After PARP Resistance: Emerging DNA Damage Response Strategies Across Solid Tumors Review Abstract Background Resistance to poly(ADP-ribose) polymerase (PARP) inhibition has intensified interest in other components of the DNA damage response and replication-stress network. Early clinical studies have evaluated ataxia telangiectasia
Thrombolysis in Intermediate-Risk Pulmonary Embolism: Who Should Receive Early Reperfusion?
Thrombolysis in Intermediate-Risk Pulmonary Embolism Who Should Receive Early Reperfusion Review Abstract Background Intermediate-risk pulmonary embolism sits in a genuinely difficult therapeutic space. On one side, you have uncomplicated pulmonary embolism managed primarily with anticoagulation. On the other side, pulmonary embolism complicated by cardiopulmonary failure that demands urgent
Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing
Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing Review Abstract Background Subclinical thyroid dysfunction is defined by biochemistry rather than symptoms. Subclinical hypothyroidism presents as an elevated thyroid-stimulating hormone (TSH) level with a free thyroxine (FT4) level that remains within the
Same-Day Total Hip and Knee Arthroplasty: The Anesthesiologist’s Expanding Role in Ambulatory ERAS
Same-Day Total Hip and Knee Arthroplasty: The Anesthesiologist's Expanding Role in Ambulatory ERAS Review Abstract Background Same-day discharge following elective primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) has become a well-established component of modern orthopedic care. Successful implementation relies on appropriate patient selection, rapid-recovery pathways, multidisciplinary
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer Review Abstract Background Evaluation of an identified suspicious skin lesion is fundamentally distinct from routine skin cancer screening. The U.S. Preventive Services Task Force (USPSTF) concludes that evidence is insufficient to
Device-Detected Subclinical Atrial Fibrillation in the Wearable Era: When Is Anticoagulation Justified?
Device-Detected Subclinical Atrial Fibrillation in the Wearable Era: When Is Anticoagulation Justified? Review Abstract Background Consumer wearables, ambulatory electrocardiographic monitors, pacemakers, implantable cardioverter-defibrillators, and implantable cardiac monitors are increasingly identifying brief and asymptomatic atrial arrhythmias. However, a photoplethysmography-based irregular-rhythm notification is not equivalent to a diagnosis
