Ibrutinib Treatment In Waldenström Macroglobulinemia Waldenström macroglobulinemia (WM) is a rare type of non-hogdkins lymphoma driven by the gene mutation MYD88L265P. Ibrutinib, the first approved treatment, is effective but can cause side effects. A study found that 27% of WM patients needed to reduce Ibrutinib doses due to side effects like
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence Overview Eyelid sebaceous gland carcinoma (SGC) is a highly malignant condition with a significant recurrence risk. This study aimed to create a predictive nomogram for SGC recurrence based on risk factors. A retrospective study involving 391 patients from one hospital (304) and grassroots hospitals (87)
Stomach Cancer: A Meta-Analysis Of Robotic Surgery Complications Gastric or stomach cancer prevalence varies significantly around the world, with higher rates in Asia, Africa, South America, and Eastern Europe. However, in the United States, stomach cancer is a growing concern due to its increased occurrence in the elderly population and its
Cognitive Behavioral Therapy In Patients With Insomnia And Chronic Fatigue Overview This study delves into the relationship between insomnia, chronic fatigue, and the response to cognitive behavioral therapy for insomnia (CBT-I). The research, a secondary analysis of data from a community-based randomized controlled trial, encompassed 1717 participants with self-reported insomnia. The primary
Non-Invasive Breast Carcinoma Treatment Outcomes Overview Non-invasive breast carcinoma, distinct from invasive forms, can lead to local recurrence post-surgery, potentially progressing to invasive carcinoma and distant metastasis, impacting breast cancer prognosis. This study, involving 93 cases among 872 primary breast cancers, assessed outcomes. Surgical interventions, radiation, and endocrine therapy were common treatments.
Control of Allergic Rhinitis and Asthma Test: A COSMIN Analysis Overview The Control of Allergic Rhinitis and Asthma Test (CARAT) serves as a patient-reported outcome measurement (PROM) to evaluate the management of asthma and allergic rhinitis (AR) within a 4-week timeframe. This systematic review aimed to assess CARAT's measurement properties. Adhering to
Pilonidal Sinus Disease And Carcinoma Prevalence Overview This study aimed to evaluate survival and recurrence rates in pilonidal sinus disease (PSD) carcinoma. A retrospective analysis of global literature identified 140 cases published between 1900 and 2022. Survival rates were 61.7% at 3 years, 59.8% at 5 years, and 53.2% at 10 years.
Sintilimab and Docetaxel Treatment Comparison in Advanced Lung Cancer Lung cancer is the leading cause of cancer death worldwide. In China, it is estimated that there were 815,563 new cases of lung cancer and 714,699 deaths in 2020. Squamous-cell non-small-cell lung cancer (sqNSCLC) accounts for about 30% of all NSCLC cases.
Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis Overview In a Phase III trial, a water-soluble ciclopirox nail hydrolacquer was evaluated for treating toenail fungal infection. Its enhanced penetration delivered higher ciclopirox concentration to the nail compared to existing lacquers. The study compared the hydrolacquer, its base formulation (vehicle), and an active control over
Allergic Rhinitis And Genetic Risk Factors Overview With the rise in atopic conditions like allergic rhinitis and the "hygiene hypothesis" in mind, numerous studies have explored whether birth order and the size of one's sibling group could act as protective factors. However, these investigations have yielded conflicting results. This study aimed to