Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy

Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Review Abstract Purpose This review examines when lifestyle intervention, metformin, and anti-obesity pharmacotherapy are most appropriate for adults with prediabetes. The objective is to clarify the role of each strategy using current clinical

Obesity as Chronic Disease: Building a Follow-up Model Like HTN/A1c

Obesity as Chronic Disease Building a Follow-up Model Like HTNA1c   Abstract Obesity is increasingly recognized as a chronic, relapsing, multifactorial disease that requires long term clinical management rather than episodic intervention. Its pathophysiology involves complex interactions among genetic predisposition, neuroendocrine regulation, metabolic adaptation, environmental

The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy?

The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy?   Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity. By simultaneously targeting

Breaking Free: How Mounjaro Helps Smokers Quit Without Nicotine Patches

Breaking Free How Mounjaro Helps Smokers Quit Without Nicotine Patches   Check back later for a possible video summary. Videos are created for most articles.     Introduction Breaking Free: How Mounjaro Helps Smokers Quit Without Nicotine Patches In 2021, almost 46 million adults in the United States reported using nicotine products, and research on the

Intelligence Of Offspring Related To Parental Obesity

Intelligence Of Offspring Related To Parental Obesity Overview The impact of maternal obesity on childhood cognitive development remains uncertain. Previous research has often lacked proper adjustments for key confounding factors, and preterm children, who represent a distinct developmental group, have been underexplored. This study aimed to investigate whether maternal prepregnancy body

Artificial Sweeteners And Health

Artificial Sweeteners And Health Carbohydrates are a significant energy source, making up forty (40%) to eighty (80%) of our daily consumption. They exist in two forms: free sugars and nonfree sugars. Nonfree sugars are found naturally in foods like fruits, vegetables, grains, and dairy. In contrast, free sugars are added during

Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy