Polypharmacy at the End of Life: Why Are So Many Patients Still Taking Statins and Bisphosphonates?

Evidence-based clinical review Polypharmacy at the End of Life: Why Are So Many Patients Still Taking Statins and Bisphosphonates? A prognosis- and goals-based approach to preventive medications, with important exceptions for recent ASCVD, high fracture risk, and active cancer indications Estimated

Continuous Glucose Monitoring Beyond Insulin: Evidence, OTC Systems, and Data Interpretation for Family Medicine

Evidence-based clinical review Continuous Glucose Monitoring Beyond Insulin Evidence, OTC Systems, and Data Interpretation for Family Medicine A practical framework for selecting professional, prescription, or over-the-counter CGM and converting an ambulatory glucose profile into safe clinical decisions Estimated reading time: 15 minutes

Blood-Based Colorectal Cancer Screening in Family Practice: Where Shield Fits Among FIT, Stool DNA, and Colonoscopy

Evidence-based clinical review Blood-Based Colorectal Cancer Screening in Family Practice: Where Shield Fits Among FIT, Stool DNA, and Colonoscopy A practical framework for average-risk adults who remain unscreened or decline preferred modalities Abstract Background: The U.S. Food

Triple Therapy for COPD: Who Benefits, Who Is at Risk for Pneumonia, and Who May Be Overtreated?

Evidence-based clinical review Triple Therapy for COPD: Who Benefits, Who Is at Risk for Pneumonia, and Who May Be Overtreated? A phenotype- and exacerbation-based approach to adding, continuing, or withdrawing inhaled corticosteroids Estimated reading time: 16 minutes

Multi-Cancer Early Detection Blood Tests in Family Practice: Clinical Promise, False Positives, and the Risks of Premature Adoption

Evidence-based clinical review Multi-Cancer Early Detection Blood Tests in Family Practice: Clinical Promise, False Positives, and the Risks of Premature Adoption Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background Multi-cancer early detection

Outpatient Community-Acquired Pneumonia in 2026: Are We Still Treating Too Broadly?

Evidence-based clinical review Outpatient Community-Acquired Pneumonia in 2026: Are We Still Treating Too Broadly? Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background Outpatient community-acquired pneumonia (CAP) is a common setting for

CGRP-Targeted Migraine Prevention as a First-Line Option: A Family Medicine Prescribing Framework

Evidence-based clinical review CGRP-Targeted Migraine Prevention as a First-Line Option: A Family Medicine Prescribing Framework Reconciling AHS and ACP guidance, selecting oral, injectable, and infusion therapies, and monitoring the updated 2026 safety warnings Estimated reading time: 17 minutes

Shorter Antibiotic Courses: How Short Is Too Short?

Evidence-based clinical review Shorter Antibiotic Courses: How Short Is Too Short? A syndrome-specific guide to finding the shortest effective duration in adults Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background

Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing

Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing Review Abstract Background Subclinical thyroid dysfunction is defined by biochemistry rather than symptoms. Subclinical hypothyroidism presents as an elevated thyroid-stimulating hormone (TSH) level with a free thyroxine (FT4) level that remains within the

Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer

Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer Review Abstract Background Evaluation of an identified suspicious skin lesion is fundamentally distinct from routine skin cancer screening. The U.S. Preventive Services Task Force (USPSTF) concludes that evidence is insufficient to

Polypharmacy at the End of Life: Why Are So Many Patients Still Taking Statins and Bisphosphonates?