Managing Diabetes in the Age of Continuous Glucose Monitoring (CGM) How Practice is Changing Review Abstract The integration of continuous glucose monitoring technology into diabetes management has significantly reshaped clinical practice over the past decade. Continuous glucose monitoring systems provide real time, dynamic assessment of interstitial glucose
Tag: Type 2 diabetes
Type 2 Diabetes Mellitus: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention
Type 2 Diabetes Mellitus as a Multifactorial Cardiometabolic Disease: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention Narrative Review Abstract Type 2 diabetes mellitus (T2DM) is a progressive, heterogeneous, multi-organ metabolic disease characterized by chronic hyperglycemia arising from inadequate insulin secretion relative to metabolic demand, usually
Obesity as Chronic Disease: Building a Follow-up Model Like HTN/A1c
Obesity as Chronic Disease Building a Follow-up Model Like HTNA1c Abstract Obesity is increasingly recognized as a chronic, relapsing, multifactorial disease that requires long term clinical management rather than episodic intervention. Its pathophysiology involves complex interactions among genetic predisposition, neuroendocrine regulation, metabolic adaptation, environmental
Why GLP-1 Receptor Agonists Are Becoming Essential Cardiovascular Drugs
Why GLP-1 Receptor Agonists Are Becoming Essential Cardiovascular Drugs Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a transformative class of medications in the management of type 2 diabetes, demonstrating an approximate 14 percent reduction in major adverse cardiovascular events. Initially developed
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility: Mechanisms, Evidence, and Clinical Implications Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are well established for the treatment of type 2 diabetes mellitus and obesity. Increasingly, reports suggest a possible association between GLP-1 RA use and
Is Type 2 Diabetes Reversible? New Research Challenges Medical Consensus
Is Type 2 Diabetes Reversible? New Research Challenges Medical Consensus Introduction The concept of type 2 diabetes reversibility represents a profound shift in the understanding and management of a condition long regarded as chronic and progressive. Diabetes remains a major global health burden, with prevalence
The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy?
The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy? Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity. By simultaneously targeting
Continuous Glucose Monitoring (CGM) for Type 2 Diabetes: Should It Be the Standard?
Dementia Risk Increase In Diabetic Patients With Poor Glycemic Control
Dementia Risk Increase In Diabetic Patients With Poor Glycemic Control Overview This study investigated the association between glycemic variability and dementia risk among 171,964 individuals with type 2 diabetes. Despite optimal glycosylated hemoglobin A1c (HbA1c) levels, variability in HbA1c over the long term was found to increase the hazard of dementia. The
Latest Research Exploring Metformin Connection To Breast Cancer
Latest Research Exploring Metformin Connection To Breast Cancer Overview This study aimed to investigate the relationship between metformin and other antidiabetic medications and the incidence of breast cancer in two large prospective cohort studies. It included 185,181 women from the Nurses' Health Study (NHS; 1994–2016) and NHSII (1995–2017). Information on type 2
