Pediatric Obesity and GLP-1 Agonists Are We Ready for Pharmacologic Therapy in Children Review Abstract Pediatric obesity has emerged as one of the most important public health challenges of the twenty-first century. Once viewed primarily as a consequence of lifestyle choices, obesity is now widely recognized
Endocrinology
Perimenopause vs Thyroid vs Mood: Sorting Symptom Overlap Efficiently
Perimenopause vs Thyroid vs Mood Sorting Symptom Overlap Efficiently Review Abstract Perimenopause, thyroid dysfunction, depression, and anxiety represent some of the most common and diagnostically challenging conditions encountered in midlife clinical practice. These disorders frequently coexist and share a broad range of overlapping symptoms, creating major complexity
Revolutionizing Diabetes Monitoring: Beyond A1C to Continuous Metabolic Profiling
Revolutionizing Diabetes Monitoring Beyond A1C to Continuous Metabolic Profiling Review Abstract Diabetes mellitus remains one of the most prevalent and challenging chronic diseases worldwide, affecting hundreds of millions of individuals and contributing significantly to cardiovascular disease, kidney failure, blindness, neuropathy, and premature mortality. Effective diabetes management
Ozempic Nation: Paradigm Shift or Public Health Mirage?
Ozempic Nation Paradigm Shift or Public Health Mirage Review Abstract The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists and related incretin-based therapies has transformed the management of obesity and type 2 diabetes mellitus. Semaglutide, marketed as Ozempic for diabetes and Wegovy for obesity, initiated a major shift in
What a Closed Loop System for Insulin Delivery Contains: Breaking Down Artificial Pancreas Technology in 2026
What a Closed Loop System for Insulin Delivery Contains: Breaking Down Artificial Pancreas Technology in 2026 Review Key Takeaways Closed-loop insulin delivery systems represent a revolutionary advancement in diabetes management, combining three essential components to automate blood sugar control and significantly improve patient outcomes.
The Vitamin D Debate: From Universal Supplement to Precision Therapy
The Vitamin D Debate: From Universal Supplement to Precision Therapy Review Abstract Vitamin D supplementation has evolved from a simple solution to rickets into one of medicine’s most debated therapeutic interventions. This paper examines the current evidence surrounding vitamin D’s role in health and disease,
Managing Diabetes in the Age of Continuous Glucose Monitoring (CGM): How Practice is Changing
Managing Diabetes in the Age of Continuous Glucose Monitoring (CGM) How Practice is Changing Review Abstract The integration of continuous glucose monitoring technology into diabetes management has significantly reshaped clinical practice over the past decade. Continuous glucose monitoring systems provide real time, dynamic assessment of interstitial glucose
From NAFLD to MASLD: Does the New Nomenclature Actually Change Care?
From NAFLD to MASLD Does the New Nomenclature Actually Change Care Review Abstract The transition from non alcoholic fatty liver disease to metabolic dysfunction associated steatotic liver disease represents a significant conceptual evolution in hepatology rather than a purely semantic change. Endorsed by major international
Type 2 Diabetes Mellitus: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention
Type 2 Diabetes Mellitus as a Multifactorial Cardiometabolic Disease: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention Narrative Review Abstract Type 2 diabetes mellitus (T2DM) is a progressive, heterogeneous, multi-organ metabolic disease characterized by chronic hyperglycemia arising from inadequate insulin secretion relative to metabolic demand, usually
Microplastics in Coffee Pods: Current Evidence and Potential Health Implications
Microplastics in Coffee Pods: Current Evidence and Potential Health Implications Key Takeaways Research reveals alarming levels of microplastic contamination in single-use coffee pods, with significant health implications for daily coffee drinkers and actionable solutions available. • A single plastic coffee pod can release over
