Endocrine Therapy Outcomes In Senior Breast Cancer Patients Overview This study investigated the management of early-stage, hormone receptor-positive, and human epidermal growth factor receptor 2 negative (HR+/HER2−) breast cancer in older women aged 70 to 90 years between 2010 and 2015. Specifically, it focused on patients who underwent lumpectomy and omitted radiation
Endocrinology
Postoperative Delirium In The NICU: Hormonal Risk Factors
Postoperative Delirium In The NICU: Hormonal Risk Factors In neurosurgery, pituitary adenoma ranks as the second most common brain tumor. Recent advances in endoscope-assisted transsphenoidal surgery have revolutionized tumor resection, reducing complications. However, postoperative complications, particularly endocrine-related issues, remain critical in neurosurgical intensive care units (NICUs). Notably, postoperative delirium, intricately linked
Onychomycosis And Diabetic Foot Syndrome
Onychomycosis And Diabetic Foot Syndrome Overview This systematic review aimed to investigate the prevalence of onychomycosis in individuals with diabetes and explore its connection to risk factors, particularly within the context of diabetic foot syndrome. Adhering to the PRISMA guidelines and utilizing the STROBE method, the study searched PubMed and Scopus databases
Hormone Disturbances in Migraine Disorder: A Meta-Analysis
Hormone Disturbances in Migraine Disorder: A Meta-Analysis Overview Migraine, a prevalent cause of disability among young adults, displays a higher incidence in females and is often accompanied by stress-related disorders, hinting at a potential link with sex and stress-related hormonal mechanisms centered around the hypothalamus. Additionally, interactions with autonomic nervous system activity
IGF-1 Levels In Pediatric Low-Grade Gliomas
IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Visual Field Defects in Patients with Pituitary Tumors
Visual Field Defects in Patients with Pituitary Tumors Overview Automated perimetry is a standardized technique for assessing the visual field, commonly using the Humphrey Field Analyser (HFA) with the 24-2 or 30-2 test patterns. This study aimed to determine if the 24-2 test pattern could yield similar outcomes as the 30-2 pattern
Levothyroxine Treatment In Patients With Thyroid Cancer
Levothyroxine Treatment In Patients With Thyroid Cancer The quest to establish effective therapy for hypothyroid obese patients remains ongoing, largely due to the challenge posed by thyrotropin-stimulating hormone (TSH) levels as a dependable marker of euthyroidism compared to nonobese patients. The positive correlation between TSH levels and body mass index (BMI)
Ocular Surgery In Infants And Post-Op Eye Drop Risks
Ocular Surgery In Infants And Post-Op Eye Drop Risks Overview This clinical observational cohort study delves into the prevalence and risk factors associated with hypothalamus-pituitary-adrenal (HPA) axis suppression in infants subjected to glucocorticoid (GC) eye drops subsequent to ocular surgery, focusing on cataract and glaucoma procedures. The research aims to discern the
Antithyroid Drug Therapy And Cardiovascular Morbidity
Antithyroid Drug Therapy And Cardiovascular Morbidity Overview The impact of thyroid function test (TFT) variability and its link to adverse health outcomes in antithyroid drug (ATD) therapy remains an unexplored area. This study aimed to investigate the relationship between TFT variability and cardiovascular morbidity during ATD therapy. Conducted at Tampere University Hospital,
Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness
Uterine Leiomyosarcoma: Systemic Therapy Effectiveness Overview Uterine leiomyosarcoma (uLMS) is an aggressive type of mesenchymal tumor linked to a bleak prognosis. The primary treatment for advanced uLMS is systemic chemotherapy, although the most effective regimen remains uncertain. To address this, we conducted an extensive analysis, including both meta-analysis and metaregression, aiming to
