Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Review Abstract Purpose This review examines when lifestyle intervention, metformin, and anti-obesity pharmacotherapy are most appropriate for adults with prediabetes. The objective is to clarify the role of each strategy using current clinical
Tag: Prediabetes
Insulin Resistance in Non-Obese Patients: The “Metabolically Obese Normal Weight” Paradox
Insulin Resistance in Non-Obese Patients: The "Metabolically Obese Normal Weight” Paradox Review Abstract Normal body mass index (BMI) has long been used as a convenient and widely accepted screening tool for assessing overweight, obesity, and cardiometabolic risk. Although BMI remains valuable for population level surveillance and initial clinical
Prediabetes Management in Family Practice: Comparative Effectiveness of Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy
Prediabetes Management in Family Practice Comparative Effectiveness of Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Abstract Prediabetes represents a critical window for intervention in the trajectory toward type 2 diabetes mellitus, offering family physicians an opportunity to prevent or significantly delay disease onset. With global
