Pediatric Cancer: An App For Pain Management

Pediatric Cancer: An App For Pain Management Pain, a pervasive and troubling symptom in childhood cancer, manifests in a significant portion of patients, affecting between 40% to 78% of those undergoing treatment. This distressing experience can arise either directly from the illness itself or as an adverse effect of the treatments

Busulfan Exposure And Malignancy Risk

Busulfan Exposure And Malignancy Risk Overview The occurrence of secondary malignancies linked to busulfan exposure is deemed low but remains insufficiently characterized. Given the rising use of this alkylating agent in pre-gene therapy conditioning for nonmalignant hematologic disorders, a more precise understanding of busulfan's potential contribution to subsequent malignancy risk is essential.

Psoriasis Risk In Children With High BMI

Psoriasis Risk In Children With High BMI Overview This study aimed to investigate the potential association between childhood body mass index (BMI) and the risk of psoriasis. Using publicly available summary statistics from genome-wide association studies (GWAS) that focused on childhood BMI in individuals of European descent (n=39,620), the researchers conducted a

Hydroxyurea: Pediatric Use in Sickle Cell Anemia

Hydroxyurea: Pediatric Use in Sickle Cell Anemia Overview This retrospective cohort study aimed to investigate the relationship between adherence to hydroxyurea treatment and clinical outcomes in children and adolescents with sickle cell anemia (SCA). The study utilized Medicaid data spanning from 2005 to 2012 across several U.S. states, focusing on children aged

Control of Allergic Rhinitis and Asthma Test: A COSMIN Analysis

Control of Allergic Rhinitis and Asthma Test: A COSMIN Analysis Overview The Control of Allergic Rhinitis and Asthma Test (CARAT) serves as a patient-reported outcome measurement (PROM) to evaluate the management of asthma and allergic rhinitis (AR) within a 4-week timeframe. This systematic review aimed to assess CARAT's measurement properties. Adhering to

Pediatric Onychomycosis Prevalence: A Systematic Review

Pediatric Onychomycosis Prevalence: A Systematic Review Overview Onychomycosis, a prevalent nail ailment in adults, has historically been considered rare in children, despite scattered and diverse data. Recent studies, however, hint at an increasing prevalence of onychomycosis in children. This review aimed to address this issue, with two authors individually scouring PubMed, Embase,

IGF-1 Levels In Pediatric Low-Grade Gliomas

IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in

Chronic Spontaneous Urticaria: Studying Age-Specific Therapies

Chronic Spontaneous Urticaria: Studying Age-Specific Therapies Overview   Chronic spontaneous urticaria (CSU) presents differently in pediatric and adult populations. A retrospective analysis of 751 CSU patients (162 pediatrics and 589 adults) revealed shorter disease duration and lower angioedema rates in pediatric cases. Adults showed higher prevalence of anti-thyroid peroxidase positivity, elevated CRP, eosinopenia,

Respiratory Syncytial Virus Infection: A Tool For Assessing Clinical Severity

Respiratory Syncytial Virus Infection: A Tool For Assessing Clinical Severity Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infection (ARTI) and the primary reason for hospitalization among infants, leading to substantial health and socioeconomic challenges. Ranging from mild cold-like symptoms to severe lower respiratory tract infection (LRTI),

Pediatric Cancer: An App For Pain Management