VEXAS Syndrome: The Newly Discovered Disorder Every Hematologist Should Know Check back later for a possible video summary. Videos are created for most articles. Abstract This paper provides a comprehensive review of VEXAS syndrome; a newly recognized, adult-onset autoinflammatory condition with a genetic basis and complex multisystem involvement, carrying significant implications for hematologists, rheumatologists, and other specialists. First
Tag: hematology
Plasmapheresis in TTP Mimics: When Are We Getting It Wrong?
Plasmapheresis in TTP Mimics: When Are We Getting It Wrong? Check back later for a possible video summary. Videos are created for most articles. Introduction Plasmapheresis has revolutionized the treatment of thrombotic thrombocytopenic purpura (TTP), reducing mortality rates from nearly 100% to less than 10–20%. Despite this progress, diagnostic uncertainty remains a
Monoclonal Antibodies in Relapsed Multiple Myeloma: The Era of Bispecifics and Beyond
Monoclonal Antibodies in Relapsed Multiple Myeloma: The Era of Bispecifics and Beyond Check back later for a possible video summary. Videos are created for most articles. Abstract This paper provides an in-depth review of monoclonal antibody (mAb) therapies in the treatment of relapsed multiple myeloma (MM), with a particular focus on bispecific antibodies
Thrombocytopenia in the ICU: Essential Guide for Clinical Hematologists
Thrombocytopenia in the ICU: Essential Guide for Clinical Hematologists Please like and subscribe if you enjoyed this video :-) Introduction Thrombocytopenia is a frequent hematologic abnormality in critically ill patients, affecting up to 67.6% at ICU admission, with an additional 14–44% developing it during their stay.
Breaking Barriers: CAR-T Therapy Shows Promise Against Solid Tumors
IRON DEFICIENCY’S IMPACT ON NEW-ONSET CHRONIC HEART FAILURE OUTCOME: DANISH HEART FAILURE REGISTRY INSIGHTS
Rusfertide Treatment For Elevated Red Blood Cell Production
Rusfertide Treatment For Elevated Red Blood Cell Production Overview Polycythemia vera is a chronic myeloproliferative disorder marked by elevated red blood cell production. Rusfertide, a peptide mimetic of the iron-regulating hormone hepcidin, has been developed to limit iron availability for erythropoiesis. However, its safety and efficacy in patients with polycythemia vera who
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients Overview Valoctocogene roxaparvovec is a gene therapy utilizing an adeno-associated virus serotype 5 (AAV5) vector, approved for treating severe hemophilia A (HA). The purpose of this summary is to present the safety and efficacy outcomes observed seven years post-dosing in a phase
Grape Syrup Improved Hemoglobin In Anemic Women
Grape Syrup Improved Hemoglobin In Anemic Women Overview Iron deficiency is the most common nutritional disorder worldwide, with anemia particularly affecting women of childbearing age. Although current treatments, such as iron supplements, are effective, they often come with side effects. This study investigates the potential of grape syrup (GS), a functional food
Promising Anemia Treatment: Cooking With Sweet Basil Leaf
Promising Anemia Treatment: Cooking With Sweet Basil Leaf Iron is an essential micronutrient critical for various physiological functions, including oxygen transport, energy production, and immune system maintenance. Adolescents, particularly girls, often face the risk of anemia due to factors like poor diet and rapid growth during puberty. This vulnerability has historically