Evidence-based clinical review Shorter Antibiotic Courses: How Short Is Too Short? A syndrome-specific guide to finding the shortest effective duration in adults Updated: September 2, 2026 | Estimated reading time: 15 minutes Abstract Background
Tag: antibiotic stewardship
Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics?
Adult Sepsis Management in Internal Medicine: Are We Overtreating, Undertreating, or Targeting the Wrong Metrics? Review Abstract Background Management of adult sepsis requires prompt decision-making amid uncertainty about infection, organ dysfunction, hemodynamic status, and treatment responsiveness. Although standardized care pathways may reduce harmful delays, indiscriminate
Antibiotic Stewardship in Pediatrics: Optimizing Diagnosis, Drug Selection, and Treatment Duration
Antibiotic Stewardship in Pediatrics: Optimizing Diagnosis, Drug Selection, and Treatment Duration Review Abstract Background Pediatric antibiotic stewardship is not synonymous with reducing antibiotic use. It is the systematic effort to prescribe antibiotics only when necessary and, when treatment is indicated, to optimize antibiotic choice, dose,
Reducing Low-Value Testing in Family Medicine: High-Yield Diagnostic Stewardship for Common Outpatient Complaints
Reducing Low-Value Testing in Family Medicine: High-Yield Diagnostic Stewardship for Common Outpatient Complaints Review Abstract Low-value diagnostic testing is common in family medicine. These tests can expose patients to false-positive results, incidental findings, and unnecessary treatments. They may also involve radiation, lead to higher costs,
The Rise of Pan-Resistant Gram-Negatives: Are We Running Out of Options?
The Rise of Pan-Resistant Gram-Negatives: Are We Running Out of Options? Review Abstract Pan-resistant gram-negative bacteria represent one of the most pressing challenges in modern medicine. These organisms exhibit resistance to virtually all available antimicrobial agents, leaving clinicians with extremely limited therapeutic options. This paper
UTI Care: When to Treat Symptoms, When to Culture, Recurrent UTI Pathways
UTI Care: When to Treat Symptoms, When to Culture, Recurrent UTI Pathways Review Abstract Urinary tract infections (UTIs) are among the most common bacterial infections encountered in clinical practice, affecting millions of patients annually. This paper examines evidence-based approaches to UTI management, focusing on three
The Return of Old Antibiotics: Are Colistin and Fosfomycin Making a Comeback?
The Return of Old Antibiotics: Are Colistin and Fosfomycin Making a Comeback? Review Abstract The rise of multidrug-resistant bacterial infections has forced clinicians to reconsider older antimicrobial agents previously abandoned due to toxicity concerns. Colistin and fosfomycin, antibiotics discovered decades ago, have experienced renewed clinical
