AI-Driven Prognostic Models in Traumatic Brain Injury Abstract Traumatic brain injury remains one of the most significant contributors to mortality and long term disability worldwide, affecting individuals across all age groups and placing a substantial burden on healthcare systems. It is a major cause of death
Neurology
Benzodiazepine Deprescribing: Evidence-Based Approaches to Tapering, Alternative Therapies, and Managing Rebound Anxiety
Benzodiazepine Deprescribing Evidence-Based Approaches to Tapering, Alternative Therapies, and Managing Rebound Anxiety Abstract Benzodiazepine deprescribing has become an increasingly important clinical priority in contemporary practice, particularly as long term benzodiazepine use remains common among patients treated for anxiety disorders, insomnia, seizure disorders, muscle spasticity, and other chronic
Sleep’s Protective Role Against Neurodegeneration: New Insights Into Brain Health Mechanisms
Sleep’s Protective Role Against Neurodegeneration: New Insights Into Brain Health Mechanisms Key Takeaways Sleep is increasingly recognized as an essential biological process for maintaining long term brain health, extending far beyond its traditional role in energy restoration and cognitive recovery. One of its most important functions
Prehospital Stroke Scales and Mobile CT Units: Worth the Investment?
Prehospital Stroke Scales and Mobile CT Units: Worth the Investment? Abstract Rapid recognition and treatment of acute stroke remain among the most important determinants of neurological recovery and long term functional outcome. Because cerebral ischemia leads to irreversible neuronal injury within minutes, every stage of early stroke
Precision Epilepsy: How Gene-Targeted Therapies Are Changing Seizure Treatment in 2026
Precision Epilepsy How Gene-Targeted Therapies Are Changing Seizure Treatment in 2026 Key Takeaways Precision epilepsy is redefining the clinical management of seizure disorders by shifting treatment strategies from generalized symptom suppression toward interventions directed at the underlying molecular and genetic causes of disease. This transition is
Brain–Computer Interfaces: From Locked-In Syndrome to Restoring Movement
Brain–Computer Interfaces: From Locked-In Syndrome to Restoring Movement Abstract Brain-computer interfaces (BCIs) represent a rapidly evolving field that directly connects the human brain to external devices. This technology shows promise for treating neurological conditions, particularly locked-in syndrome and motor impairments resulting from spinal cord
Comorbid Insomnia: New Research Reveals Bidirectional Mental Health Links
Comorbid Insomnia New Research Reveals Bidirectional Mental Health Links Introduction Comorbid insomnia represents a substantial and often underrecognized public health challenge, affecting an estimated 25 million individuals in the United States each year and contributing to approximately $100 billion in annual healthcare expenditures. Sleep
Targeting α-Synuclein: The Next Frontier in Parkinson’s Therapy
Targeting α-Synuclein The Next Frontier in Parkinson’s Therapy Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting an estimated 10 million individuals worldwide. Its prevalence is expected to rise substantially with population aging, creating an expanding clinical and socioeconomic
Postoperative Delirium and Brain Health: Can the Anesthesiologist Prevent Dementia?
Postoperative Delirium and Brain Health Can the Anesthesiologist Prevent Dementia Abstract Postoperative delirium has emerged as a major concern in perioperative medicine, particularly among older adults undergoing surgical procedures. Characterized by an acute and fluctuating disturbance in attention, awareness, and cognition, postoperative delirium affects
CRISPR and Gene Editing in Neurodegenerative Diseases: Current Applications and Future Therapeutic Potential
CRISPR and Gene Editing in Neurodegenerative Diseases Current Applications and Future Therapeutic Potential Abstract Neurodegenerative diseases continue to pose profound challenges to modern medicine, affecting millions of individuals worldwide and contributing significantly to disability, mortality, and healthcare expenditure. Disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease,
