Evidence-based clinical review The Neurology of Dysautonomia POTS, Orthostatic Intolerance, and Autonomic Testing in 2026 A Practical Neurologic Framework for Distinguishing POTS From Other Orthostatic Syndromes and Selecting Active Stand, Tilt-Table, Reflex, Sudomotor, and Small-Fiber Studies Estimated reading time: 15 minutes
Author: Nancy Ogbonna
Shorter Antibiotic Courses: How Short Is Too Short?
Thrombolysis in Intermediate-Risk Pulmonary Embolism: Who Should Receive Early Reperfusion?
Thrombolysis in Intermediate-Risk Pulmonary Embolism Who Should Receive Early Reperfusion Review Abstract Background Intermediate-risk pulmonary embolism sits in a genuinely difficult therapeutic space. On one side, you have uncomplicated pulmonary embolism managed primarily with anticoagulation. On the other side, pulmonary embolism complicated by cardiopulmonary failure that demands urgent
Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing
Subclinical Thyroid Dysfunction in Family Practice: Evidence, Treatment Thresholds, and Counseling for Patient-Requested Testing Review Abstract Background Subclinical thyroid dysfunction is defined by biochemistry rather than symptoms. Subclinical hypothyroidism presents as an elevated thyroid-stimulating hormone (TSH) level with a free thyroxine (FT4) level that remains within the
Same-Day Total Hip and Knee Arthroplasty: The Anesthesiologist’s Expanding Role in Ambulatory ERAS
Same-Day Total Hip and Knee Arthroplasty: The Anesthesiologist's Expanding Role in Ambulatory ERAS Review Abstract Background Same-day discharge following elective primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) has become a well-established component of modern orthopedic care. Successful implementation relies on appropriate patient selection, rapid-recovery pathways, multidisciplinary
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer
Skin Cancer Detection and Procedural Decisions in Family Practice: When to Biopsy, Use Cryotherapy, or Refer Review Abstract Background Evaluation of an identified suspicious skin lesion is fundamentally distinct from routine skin cancer screening. The U.S. Preventive Services Task Force (USPSTF) concludes that evidence is insufficient to
Device-Detected Subclinical Atrial Fibrillation in the Wearable Era: When Is Anticoagulation Justified?
Device-Detected Subclinical Atrial Fibrillation in the Wearable Era: When Is Anticoagulation Justified? Review Abstract Background Consumer wearables, ambulatory electrocardiographic monitors, pacemakers, implantable cardioverter-defibrillators, and implantable cardiac monitors are increasingly identifying brief and asymptomatic atrial arrhythmias. However, a photoplethysmography-based irregular-rhythm notification is not equivalent to a diagnosis
CIDP Overdiagnosis and IVIG Stewardship: Are We Treating the Right Patients for the Right Duration?
CIDP Overdiagnosis and IVIG Stewardship: Are We Treating the Right Patients for the Right Duration? Review Abstract Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a highly treatable immune-mediated neuropathy. However, establishing the diagnosis requires a careful integration of the clinical phenotype, electrodiagnostic findings, appropriate supportive evidence,
Frailty Before the ICU: Using Frailty Scores to Guide Escalation Without Turning Them Into Gatekeepers
Frailty Before the ICU: Using Frailty Scores to Guide Escalation Without Turning Them Into Gatekeepers Review Abstract Purpose: Frailty has emerged as an important predictor of adverse outcomes in hospitalized and critically ill adults, particularly among older patients with multiple chronic conditions. As healthcare systems increasingly care
Melanoma Screening in the AI Era: Why Dermatologists Remain the Clinical Standard and AI Should Stay an Adjunct
Melanoma Screening in the AI Era: Why Dermatologists Remain the Clinical Standard and AI Should Stay an Adjunct Review Abstract Purpose: Melanoma remains one of the most aggressive forms of skin cancer, accounting for a disproportionate number of skin cancer related deaths despite representing a relatively small
