Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Review Abstract Purpose This review examines when lifestyle intervention, metformin, and anti-obesity pharmacotherapy are most appropriate for adults with prediabetes. The objective is to clarify the role of each strategy using current clinical
Author: Nancy Ogbonna
Ultra-Low-Dose CT: How Low Can We Go Without Losing the Diagnosis?
Ultra-Low-Dose CT: How Low Can We Go Without Losing the Diagnosis? Review A Task-Based Review for Clinicians Abstract Purpose: This review examines the clinical role of ultra-low-dose computed tomography (ULDCT), with emphasis on the circumstances in which radiation reduction can preserve diagnostic performance and those
Urinary Tract Infection Is a Clinical Diagnosis: Avoiding Overdiagnosis From Asymptomatic Bacteriuria, Contamination, and Culture-Driven Treatment in Primary Care
Urinary Tract Infection Is a Clinical Diagnosis: Avoiding Overdiagnosis From Asymptomatic Bacteriuria, Contamination, and Culture-Driven Treatment in Primary Care Review Abstract Purpose Urinary tract infection is among the most frequently diagnosed bacterial infections in primary care and remains a major reason for outpatient antibiotic prescribing.
Vaginal Symptoms in Primary Care: A Test-Directed Approach to Candidiasis, Bacterial Vaginosis, and Trichomoniasis
Vaginal Symptoms in Primary Care: A Test-Directed Approach to Candidiasis, Bacterial Vaginosis, and Trichomoniasis Review Abstract Purpose Symptoms associated with vaginitis, including vaginal discharge, odor, pruritus, burning, irritation, dysuria, and dyspareunia, are common reasons for primary care, urgent care, gynecology, and sexual health visits. These
Mesh in Hernia Repair: Is the Pendulum Swinging Back or Just Getting Smarter?
Mesh in Hernia Repair: Evolving Strategies and Contemporary Perspectives Review Abstract Purpose: This review examines the evolving role of surgical mesh in contemporary hernia repair, focusing on guideline recommendations, device safety, patient selection, wound environment, operative technique, and practical clinical decision-making. Methodology: This narrative review
Environmental and Lifestyle Hematology: How Air Pollution and Chronic Stress Influence Hematopoiesis, Inflammation, and Vascular Risk
Environmental and Lifestyle Hematology: The Influence of Air Pollution and Chronic Stress on Hematopoiesis, Inflammation, and Vascular Risk Review Abstract Purpose: This review examines how fine particulate air pollution and chronic psychosocial stress may influence hematopoiesis, inflammatory leukocyte production, coagulation biology, clonal hematopoiesis, and cardiovascular risk.
HFpEF: From Therapeutic Desert to Crowded Treatment Space
Heart Failure with Preserved Ejection Fraction: Transitioning from Limited Therapeutic Options to an Expanding Treatment Landscape Review Abstract Purpose Heart failure with preserved ejection fraction (HFpEF) remains one of the most heterogeneous and diagnostically challenging syndromes in cardiovascular medicine. This review examines the evolving management
Perioperative Anaphylaxis: Preparing for the Next Rocuronium, Chlorhexidine, or Antibiotic Reaction
Perioperative Anaphylaxis: Preparing for Rocuronium, Chlorhexidine, and Antibiotic Reactions Review Abstract Purpose: This review examines perioperative anaphylaxis, with emphasis on practical preparedness for reactions involving neuromuscular blocking agents, chlorhexidine, and perioperative antibiotics. Methodology: This narrative review integrates current perioperative anaphylaxis guidance, drug-allergy practice parameters, official
Normal Pressure Hydrocephalus: The Reversible Dementia We Still Miss
Normal Pressure Hydrocephalus: The Reversible Dementia We Still Miss Review Abstract Purpose: This review examines normal pressure hydrocephalus (NPH), emphasizing timely clinical recognition, evidence-based diagnostic strategies, patient selection for surgical intervention, anticipated outcomes after cerebrospinal fluid shunting, medication-related confounders, and procedural safety considerations. As one
Permanent Contraception: Salpingectomy vs Tubal Ligation. What’s Your Default Now?
Permanent Contraception: Salpingectomy Versus Tubal Ligation - Current Default Approaches Review Abstract Purpose: This review evaluates complete bilateral salpingectomy and traditional tubal ligation, tubal occlusion, or partial salpingectomy as surgical options for permanent contraception. It compares contraceptive effectiveness, perioperative safety, operative feasibility, ovarian function, cancer-risk
