Fluorescence-Guided Surgery: From Indocyanine Green to Tumor-Specific Fluorophores in 2026

Fluorescence-Guided Surgery: From Indocyanine Green to Tumor-Specific Fluorophores in 2026 Review Key Takeaways Fluorescence-guided surgery (FGS) is reshaping oncologic surgery by enabling real-time molecular visualization of tumors and critical anatomical structures. The field has evolved from non-specific fluorescent dyes toward highly targeted fluorophores capable of identifying malignant

Insomnia in Primary Care: Implementation of CBT

Insomnia in Primary Care: Implementation of CBT Review Abstract Insomnia is one of the most prevalent sleep disorders encountered in primary care and affects approximately 10–15% of adults worldwide. Chronic insomnia is associated with substantial impairments in daytime functioning, increased healthcare utilization, psychiatric and medical comorbidity, and reduced

Ozempic Nation: Paradigm Shift or Public Health Mirage?

Ozempic Nation Paradigm Shift or Public Health Mirage Review Abstract The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists and related incretin-based therapies has transformed the management of obesity and type 2 diabetes mellitus. Semaglutide, marketed as Ozempic for diabetes and Wegovy for obesity, initiated a major shift in

IBS Next-Generation Therapies: Low FODMAP Diets, Neuromodulators, Digital Cognitive Behavioral Therapy, and Microbiome-Based Interventions

IBS Next-Generation Therapies: Low FODMAP Diets, Neuromodulators, Digital Cognitive Behavioral Therapy, and Microbiome-Based Interventions Review Abstract Background Irritable bowel syndrome (IBS) is a chronic disorder of gut–brain interaction characterized by abdominal pain associated with altered bowel habits. Conventional therapies often provide incomplete symptom relief, leading to

Foundation Models for Imaging: Are We Entering the Era of ‘Generalist’ Radiology AI?

Foundation Models for Imaging: Are We Entering the Era of ‘Generalist’ Radiology AI? Review Abstract Foundation models represent a transformative development in artificial intelligence that has the potential to fundamentally reshape the field of medical imaging. Unlike traditional machine learning systems that are designed and

MS Phenotypes: Why the Current Classification System May Be Failing Patients

MS Phenotypes: Why the Current Classification System May Be Failing Patients Review Key Takeaways The traditional classification system for multiple sclerosis, established in 1996 by the United States National Multiple Sclerosis Society, continues to shape clinical practice, therapeutic decision making, and clinical trial design nearly three

Pediatric Mental Health Crisis: Navigating the Surge in Anxiety and Depression

Pediatric Mental Health Crisis Navigating the Surge in Anxiety and Depression Review Abstract The current state of pediatric mental health has emerged as one of the most urgent and complex challenges confronting healthcare systems worldwide. Anxiety and depressive disorders among children and adolescents have increased substantially over the past

Post-Polypectomy Surveillance: Are We Over-Scoping Patients (and Under-Scoping the High-Risk Ones)?

Post-Polypectomy Surveillance: Are We Over-Scoping Patients (and Under-Scoping the High-Risk Ones)? Review Key Takeaways Post polypectomy surveillance is a critical component of colorectal cancer prevention strategies, aimed at reducing the incidence of interval colorectal cancers through timely follow up colonoscopy after adenoma removal. However, current surveillance practices

Robotic Surgery Beyond Urology: Which Procedures Are Finally Worth the Docking Time?

Robotic Surgery Beyond Urology: Which Procedures Are Finally Worth the Docking Time? Review Abstract Robotic surgery has undergone substantial expansion since its early adoption in urology, evolving into a widely utilized surgical platform across numerous specialties including general surgery, gynecology, cardiothoracic surgery, colorectal surgery, and orthopedics. Initially

Thrombosis and Cancer Immunotherapy: The Next Frontier of Thromboinflammation

Thrombosis and Cancer Immunotherapy The Next Frontier of Thromboinflammation Review Abstract Cancer immunotherapy has fundamentally transformed the treatment landscape across multiple malignancies, offering durable responses and prolonged survival in patients with previously limited therapeutic options. Immune checkpoint inhibitors, chimeric antigen receptor T cell therapies, bispecific antibodies,

Fluorescence-Guided Surgery: From Indocyanine Green to Tumor-Specific Fluorophores in 2026