Resistant Hypertension Gets Personal: Aldosterone, Renin, and the Renewed Secondary Workup Review Abstract Purpose: Resistant hypertension remains a significant clinical challenge and is associated with a markedly increased risk of cardiovascular disease, chronic kidney disease progression, stroke, heart failure, and premature mortality. Despite the availability of multiple
Author: Nancy Ogbonna
Vaccines and Catch-Up in 2026: Schedule Navigation, Documentation, and Vaccine Confidence for Clinicians
Vaccines and Catch-Up in 2026: Schedule Navigation, Documentation, and Vaccine Confidence for Clinicians Review Abstract Purpose: This review provides a comprehensive overview of contemporary vaccine practice in 2026, with emphasis on immunization schedule navigation, catch up vaccination, documentation standards, vaccine safety, product specific recommendations, and evidence based communication
Vestibular Migraine in Neurology Clinics: The Great Mimicker Behind Recurrent Vertigo
Vestibular Migraine in Neurology Clinics The Great Mimicker Behind Recurrent Vertigo Review Abstract Purpose: Vestibular migraine is increasingly recognized as one of the most common neurological causes of recurrent episodic vertigo and dizziness, yet it remains substantially underdiagnosed and frequently misclassified in routine clinical practice. Patients
Quantitative Neuromuscular Monitoring: Why Are We Still Guessing at Recovery?
Quantitative Neuromuscular Monitoring Why Are We Still Guessing at Recovery Review Abstract Purpose: This review critically evaluates the scientific rationale, current evidence, professional guideline recommendations, and practical implementation of quantitative neuromuscular monitoring during recovery from neuromuscular blockade, with particular emphasis on patients receiving nondepolarizing neuromuscular blocking
HIV in the Era of Long-Acting Injectables: Redefining Adherence Without Abandoning Follow-Up
HIV in the Era of Long-Acting Injectables: Redefining Adherence Without Abandoning Follow-Up Reviewed and updated July 29, 2026 Abstract Purpose: This review examines how long-acting injectable antiretroviral therapy and injectable HIV pre-exposure prophylaxis are changing treatment, prevention, and adherence frameworks in HIV care. Methodology: The
Menin Inhibitors in AML: Targeting KMT2A-Rearranged and NPM1-Mutated Disease
Menin Inhibitors in AML: Targeting KMT2A-Rearranged and NPM1-Mutated Disease Review Abstract Purpose Acute myeloid leukemia (AML) is a heterogeneous group of hematologic malignancies defined increasingly by recurrent molecular and cytogenetic abnormalities. KMT2A rearrangements and NPM1 mutations identify biologically distinct leukemias that frequently rely on menin-dependent
Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy
Prediabetes in 2026: Evidence Thresholds for Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Review Abstract Purpose This review examines when lifestyle intervention, metformin, and anti-obesity pharmacotherapy are most appropriate for adults with prediabetes. The objective is to clarify the role of each strategy using current clinical
Ultra-Low-Dose CT: How Low Can We Go Without Losing the Diagnosis?
Ultra-Low-Dose CT: How Low Can We Go Without Losing the Diagnosis? Review A Task-Based Review for Clinicians Abstract Purpose: This review examines the clinical role of ultra-low-dose computed tomography (ULDCT), with emphasis on the circumstances in which radiation reduction can preserve diagnostic performance and those
Urinary Tract Infection Is a Clinical Diagnosis: Avoiding Overdiagnosis From Asymptomatic Bacteriuria, Contamination, and Culture-Driven Treatment in Primary Care
Urinary Tract Infection Is a Clinical Diagnosis: Avoiding Overdiagnosis From Asymptomatic Bacteriuria, Contamination, and Culture-Driven Treatment in Primary Care Review Abstract Purpose Urinary tract infection is among the most frequently diagnosed bacterial infections in primary care and remains a major reason for outpatient antibiotic prescribing.
Vaginal Symptoms in Primary Care: A Test-Directed Approach to Candidiasis, Bacterial Vaginosis, and Trichomoniasis
Vaginal Symptoms in Primary Care: A Test-Directed Approach to Candidiasis, Bacterial Vaginosis, and Trichomoniasis Review Abstract Purpose Symptoms associated with vaginitis, including vaginal discharge, odor, pruritus, burning, irritation, dysuria, and dyspareunia, are common reasons for primary care, urgent care, gynecology, and sexual health visits. These
