IBS Next-Generation Therapies: Low FODMAP Diets, Neuromodulators, Digital Cognitive Behavioral Therapy, and Microbiome-Based Interventions

Abstract Background Irritable bowel syndrome (IBS) is a chronic disorder of gut–brain interaction characterized by abdominal pain associated with altered bowel habits. Conventional therapies often provide incomplete symptom relief, leading to increasing interest in next-generation approaches that target dietary triggers, central and enteric neuromodulation, psychological factors, and the intestinal microbiome. Objective This review evaluates

IBS Next-Generation Therapies: Low FODMAP Diets, Neuromodulators, Digital Cognitive Behavioral Therapy, and Microbiome-Based Interventions