Neuroinflammation in Depression: Biomarker or Target?

Neuroinflammation in Depression: Biomarker or Target?  Abstract Major depressive disorder (MDD) remains a leading global cause of disability, yet its underlying pathophysiology is incompletely understood. Increasing evidence implicates immune and inflammatory processes in the onset, progression, and treatment response of depression. This review synthesizes current

Continuous Glucose Monitoring (CGM) for Type 2 Diabetes: Should It Be the Standard?

Continuous Glucose Monitoring (CGM) for Type 2 Diabetes: Should It Be the Standard?   Abstract Continuous glucose monitoring (CGM) has evolved into one of the most notable innovations in modern diabetes care. While its benefits are well established in type 1 diabetes, growing evidence suggests

GLP-1 Agonists for NASH Treatment: New Clinical Evidence Reveals Surprising Results

GLP-1 Agonists for NASH Treatment: New Clinical Evidence Reveals Surprising Results   Introduction Non-alcoholic fatty liver disease (NAFLD) has emerged as a major global health concern, affecting approximately one in four individuals worldwide. It is now recognized as the most common cause of

Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025

Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025   Introduction Subclinical Cushing’s syndrome (SCS) presents a striking diagnostic paradox. While the classic form of Cushing’s syndrome is rare, with an estimated prevalence of approximately 1 case per 100,000 individuals, subclinical Cushing’s

The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review

The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review   Abstract Background:Chronic kidney disease (CKD) affects more than 10% of the global population and is increasingly recognized as a critical public health challenge. Its rising prevalence is largely attributed to

Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment?

Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment?   Abstract Background and Purpose:The global incidence of thyroid cancer has risen sharply over the past three decades. Data indicate that annual incidence increased from 5.0 cases per 100,000 individuals in 1975 to 14.6 cases per

Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising?

Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising?   Abstract Endocrine-disrupting chemicals (EDCs) have emerged as a notable concern in reproductive health, with increasing evidence linking exposure to reduced fertility in both men and women. These compounds, which include a broad spectrum of

Autoimmunity and COVID Vaccines: Risk of Flares or Protective Benefits? A Comprehensive Analysis for Academic and Industry Experts

Autoimmunity and COVID Vaccines: Risk of Flares or Protective Benefits? A Comprehensive Analysis for Academic and Industry Experts  Abstract The link between getting a COVID-19 vaccine and having an autoimmune disease is an intricate blend of immunology, public health, and clinical practice. This analytical review