The Surprising Truth: Why Open Surgery Might Be Better Than Minimally Invasive Options Introduction The open surgery definition encompasses direct physical access to organs and tissues through larger incisions, a technique that remains essential despite the technological revolution in surgical care. While minimally invasive
The Opioid-Free OR: Can Multimodal Anesthesia Eliminate Narcotics Entirely?
The Opioid-Free OR: Can Multimodal Anesthesia Eliminate Narcotics Entirely? Abstract The growing opioid crisis has pushed healthcare systems worldwide to explore alternative pain management strategies, particularly in the perioperative setting. This paper examines the feasibility and effectiveness of opioid-free anesthesia through multimodal approaches
Same-Day Discharge After Major Surgery: How Far Can We Safely Push ERAS?
Same-Day Discharge After Major Surgery: How Far Can We Safely Push ERAS? Abstract Enhanced Recovery After Surgery (ERAS) protocols have changed how we think about postoperative care. These evidence-based approaches aim to reduce complications, speed recovery, and help patients return to their normal
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility: Mechanisms, Evidence, and Clinical Implications Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are well established for the treatment of type 2 diabetes mellitus and obesity. Increasingly, reports suggest a possible association between GLP-1 RA use and
Tranexamic Acid in Non-Trauma Cases: The Hidden Risks You Should Know
Tranexamic Acid in Non-Trauma Cases The Hidden Risks You Should Know Introduction Tranexamic acid is a synthetic antifibrinolytic agent widely used to reduce bleeding by inhibiting plasminogen activation and fibrin degradation. Its efficacy in trauma related hemorrhage has led to broad acceptance across emergency
The Great Propofol Debate: Are We Too Dependent on a Single Drug?
The Great Propofol Debate Are We Too Dependent on a Single Drug Abstract Since its introduction into clinical practice in the 1980s, propofol has become a cornerstone of modern anesthesia and procedural sedation. Its rapid onset of action, short context sensitive half time, and predictable recovery profile
Silent Inflammation: The Hidden Driver of Multisystem Chronic Disease?
Silent Inflammation The Hidden Driver of Multisystem Chronic Disease Abstract Chronic low grade inflammation, often referred to as silent inflammation, is increasingly recognized as a persistent inflammatory state that occurs in the absence of the classical signs and symptoms associated with acute inflammation.
Rare Disease Diagnosis: The Promise of Whole-Genome Sequencing in Pediatrics
Rare Disease Diagnosis The Promise of Whole-Genome Sequencing in Pediatrics Abstract Rare diseases collectively affect millions of children worldwide and represent a significant source of morbidity, mortality, and long term disability. Although individual rare disorders have low prevalence, their cumulative impact places a substantial
Precision Endocrinology: How Genomic Testing Improves Thyroid Treatment Outcomes
Precision Endocrinology How Genomic Testing Improves Thyroid Treatment Outcomes Introduction Precision endocrinology represents a paradigm shift in the management of thyroid disorders, grounded in an expanding body of genetic and molecular evidence. Large scale genetic studies have demonstrated that approximately 57 to 71 percent
New Frontiers in Male Hypogonadism: Are We Over-Treating Low Testosterone?
New Frontiers in Male Hypogonadism Are We Over-Treating Low Testosterone Abstract Male hypogonadism has emerged as one of the most intensively debated topics in men’s health over the past two decades. Advances in laboratory testing, increased awareness of androgen deficiency, and widespread direct to consumer marketing have
