Investigating the Rapid Rise in Early-Onset Cancer Incidence Among Adolescents and Adults Under 50 in the United States: Trends, Risk Factors, Screening Gaps, Environmental Exposures, Lifestyle Drivers, and Implications for Prevention and Public Health Policy Abstract The incidence of early-onset cancer among individuals under 50 years
AI Companions and Human Connection: How Artificial Intelligence Is Changing Loneliness
AI Companions & Human Connection: How Artificial Intelligence Is Changing Loneliness Abstract The emergence of artificial intelligence companions represents a fundamental shift in how humans address loneliness and social isolation. This paper examines the growing prevalence of AI companions, their impact on human psychological
The Dopamine Paradox: Why Pleasure Often Undermines Motivation
The Dopamine Paradox: Why Pleasure Often Undermines Motivation Abstract Purpose: This paper examines the counterintuitive relationship between dopamine-mediated pleasure and human motivation, exploring how immediate gratification can diminish long-term goal pursuit. The analysis focuses on neurobiological mechanisms underlying motivation regulation and their clinical
The Cancer Risk Paradox of Anti-Aging Therapies
The Cancer Risk Paradox of Anti-Aging Therapies Abstract The relationship between anti-aging interventions and cancer risk presents a complex biological paradox that demands careful examination by healthcare practitioners. While many anti-aging therapies aim to promote cellular health and longevity, they may inadvertently create conditions that
Beyond Thrombectomy: Latest Advances in Large Vessel Occlusion Therapy
Beyond Thrombectomy: Latest Advances in Large Vessel Occlusion Therapy Introduction Stroke from large vessel occlusion remains a devastating neurological emergency affecting millions worldwide. According to the American Heart Association, stroke ranks as the fourth leading cause of death in the United States, with
AI in the Cath Lab: Clinical Breakthrough or Expensive Decision Support?
AI in the Cath Lab: Clinical Breakthrough or Expensive Decision Support? Abstract The integration of artificial intelligence (AI) into cardiac catheterization laboratories represents a major shift in cardiovascular medicine. This analysis examines the clinical effectiveness, economic impact, and practical implementation of AI systems
AI in Internal Medicine: Can Algorithms Outperform the Clinical Intuition of Experienced Physicians?
AI in Internal Medicine: Can Algorithms Outperform the Clinical Intuition of Experienced Physicians? Abstract This paper examines the growing role of artificial intelligence in internal medicine and addresses the critical question of whether algorithmic approaches can surpass the clinical intuition developed by experienced physicians
Medical Alert Watch Technology: From Detection to Emergency Response in Minutes
Medical Alert Watch Technology: From Detection to Emergency Response in Minutes Introduction Falls represent a major public health concern among older adults, with more than one in four individuals aged 65 years and older experiencing at least one fall annually. These events are associated
Why Biomarker-Driven Treatment Fails: The Hidden Role of Histology
Why Biomarker-Driven Treatment Fails The Hidden Role of Histology Introduction Biomarker-driven treatment has fundamentally transformed oncology, ushering in an era of precision medicine in which therapeutic decisions are increasingly guided by the molecular characteristics of tumors rather than their anatomical origin alone. A
Targeting the Bone Marrow Microenvironment in Myeloma and Acute Myeloid Leukemia: Novel Therapeutic Approaches and Clinical Implications
Targeting the Bone Marrow Microenvironment in Myeloma and Acute Myeloid Leukemia Novel Therapeutic Approaches and Clinical Implications Abstract The bone marrow microenvironment is increasingly recognized as a central determinant in the initiation, progression, and therapeutic resistance of hematologic malignancies, particularly multiple myeloma and acute myeloid leukemia
