Resistant Starch and Short-Chain Fatty Acids: A Comprehensive Review of Physiologic Mechanisms and Clinical Relevance Comprehensive Guide Abstract Resistant starch represents a distinct category of dietary carbohydrate that escapes digestion in the small intestine and undergoes fermentation by colonic bacteria. This process generates short-chain fatty
Coronary Artery Calcium–Guided Prevention and Microbiome-Centered Nutrition
Coronary Artery Calcium–Guided Prevention and Microbiome-Centered Nutrition: A Physician-Focused Review Integrating the Clinical Framework of William Davis, MD Quick Summary CAC is most useful when you’re on the fence. In borderline/intermediate-risk patients—or when risk markers conflict—CAC can clarify preventive intensity and improve
Preventing the Next Pandemic: Critical Insights from SARS-CoV-2 Surveillance Systems
Preventing the Next Pandemic Critical Insights from SARS-CoV-2 Surveillance Systems Introduction Preventing the next global pandemic requires a clear understanding of the profound and multifaceted impact of SARS-CoV-2, the virus responsible for COVID-19. Since its emergence, SARS-CoV-2 has infected millions of people worldwide and caused
Noninvasive Prenatal Testing (NIPT): What’s Next After Aneuploidy?
Noninvasive Prenatal Testing (NIPT) What’s Next After Aneuploidy Abstract Noninvasive prenatal testing has fundamentally reshaped prenatal screening by enabling highly accurate detection of fetal chromosomal abnormalities through analysis of cell free fetal DNA circulating in maternal blood. Since its clinical introduction, NIPT has been widely
Expert Guide: Managing Cardiovascular-Kidney-Metabolic Syndrome in Clinical Practice
Expert Guide Managing Cardiovascular-Kidney-Metabolic Syndrome in Clinical Practice Introduction Cardiovascular kidney metabolic syndrome represents one of the most urgent and complex health challenges of the modern era. The global burden of cardiovascular disease continues to rise at an alarming pace, with prevalence increasing from approximately
Beyond the Golden Hour in Trauma Care: New Evidence Questions Traditional Time Windows
Beyond the Golden Hour in Trauma Care New Evidence Questions Traditional Time Windows Introduction The concept of the golden hour has long been a foundational principle in trauma and emergency medicine, emphasizing the urgency of definitive care within the first 60 minutes following
Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era?
Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era Abstract The introduction of biologic disease modifying antirheumatic drugs has fundamentally reshaped the management of rheumatoid arthritis over the past two decades. These agents, in combination with conventional synthetic therapies and treat to target strategies, have significantly
Are Operating Rooms Ready for Surgical AI? New Data Reveals Critical Insights
Are Operating Rooms Ready for Surgical AI New Data Reveals Critical Insights Introduction Surgical decision making remains a critical determinant of patient outcomes, with lapses in judgment consistently identified by surgeons as the most common cause of major intraoperative errors. These judgment related failures represent
The Surprising Truth: Why Open Surgery Might Be Better Than Minimally Invasive Options
The Surprising Truth: Why Open Surgery Might Be Better Than Minimally Invasive Options Introduction The open surgery definition encompasses direct physical access to organs and tissues through larger incisions, a technique that remains essential despite the technological revolution in surgical care. While minimally invasive
The Opioid-Free OR: Can Multimodal Anesthesia Eliminate Narcotics Entirely?
The Opioid-Free OR: Can Multimodal Anesthesia Eliminate Narcotics Entirely? Abstract The growing opioid crisis has pushed healthcare systems worldwide to explore alternative pain management strategies, particularly in the perioperative setting. This paper examines the feasibility and effectiveness of opioid-free anesthesia through multimodal approaches
