Heart Failure Polygenic Risk Predictions Overview This study explores the genetic associations and risk prediction capabilities of polygenic risk scores (PRSs) derived from risk factors shared with heart failure (HF) in bi-racial populations. The risk factors considered include atrial fibrillation (AF), body mass index (BMI), coronary heart disease (CHD), systolic blood pressure
Family Practice Medicine
Ketamine Infusion In The Treatment Of Chronic Pain
Ketamine Infusion In The Treatment Of Chronic Pain The relentless nature of chronic pain not only causes physical discomfort but also takes a heavy emotional toll, impacting quality of life and daily functioning. Despite the widespread prevalence of chronic pain, traditional medications frequently prove inadequate in delivering sustained and satisfactory relief
Chronic Pain In Adulthood Linked To Adverse Childhood Experiences
Chronic Pain In Adulthood Linked To Adverse Childhood Experiences Overview This study aimed to elucidate the complex interplay between adverse childhood experiences (ACEs), anxiety, and chronic pain in adults through a systematic literature review (SLR) and meta-analysis. The narrative synthesis of findings revealed a substantial association between ACEs, anxiety, and chronic pain
First Seizure Effects on Cognition in Adults
First Seizure Effects on Cognition in Adults Overview Investigating cognitive and psychological functioning in adults after their first seizure, prior to epilepsy diagnosis and treatment, is crucial for understanding the early manifestations of neuropsychological comorbidities associated with chronic epilepsy. In this study, conducted through a telehealth-based prospective design, cognition, mood, and anxiety
Op Koers Online Program: Assistance For Parents Of Pediatric Cancer Patients
Op Koers Online Program: Assistance For Parents Of Pediatric Cancer Patients This research addresses the challenges faced by parents of children with cancer, emphasizing the stress and uncertainty associated with treatments and long-term effects. The study, anchored in the disability-stress-coping model, highlights the crucial role of coping skills in mediating well-being.
Hearing Testing Using At-Home Smartphone Apps
Hearing Testing Using At-Home Smartphone Apps Over 20% of the world's population has hearing loss, with 5% facing communication challenges. This disability causes psychosocial burdens, health issues, and economic losses due to decreased productivity. Early detection and remote monitoring can help reduce these negative effects and aid clinical diagnosis and research. Pure
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis Overview This study examined the efficacy and safety of abrocitinib, a treatment for moderate-to-severe atopic dermatitis (AD), specifically focusing on patients with allergic comorbidities. Data from phase 2b and phase 3 trials were analyzed, pooling information from patients who received abrocitinib or
Pediatric Cancer: An App For Pain Management
Pediatric Cancer: An App For Pain Management Pain, a pervasive and troubling symptom in childhood cancer, manifests in a significant portion of patients, affecting between 40% to 78% of those undergoing treatment. This distressing experience can arise either directly from the illness itself or as an adverse effect of the treatments
Open-Angle Glaucoma And Glaucoma Filtration Surgery
Open-Angle Glaucoma And Glaucoma Filtration Surgery Overview This population-based historic cohort study, spanning from 1997 to 2017, aimed to investigate the rate and risk factors associated with glaucoma filtration surgery (GFS) in individuals newly diagnosed with open-angle glaucoma (OAG) aged 45 and above. The cohort comprised 9420 patients diagnosed with OAG between
Piclidenoson In The Treatment Of Plaque Psoriasis
Piclidenoson In The Treatment Of Plaque Psoriasis Overview The study focused on evaluating the effectiveness and safety of piclidenoson (CF101), an orally bioavailable agonist for the A3 adenosine receptor (A3AR), in treating moderate-to-severe plaque psoriasis. The A3AR is known to be overexpressed in the skin and peripheral blood mononuclear cells of individuals
