Spotlight On Heart Failure Pathophysiology: Coronary Microvascular Dysfunction

Spotlight On Heart Failure Pathophysiology: Coronary Microvascular Dysfunction Overview  In the comprehensive investigation of heart failure with preserved ejection fraction (HFpEF), a multitude of underlying mechanisms were explored, among which coronary microvascular dysfunction (CMD) emerged as a pivotal contributor to the pathophysiology. Through a rigorous systematic review and meta-analysis, the research aimed

Fatty Acid Intake And Reduced Cardiovascular Event Risk

Fatty Acid Intake And Reduced Cardiovascular Event Risk Overview Recent research has raised questions about the purported benefits of Omega-3 fatty acids in improving endothelial thickness and preventing cardiovascular diseases like coronary atherosclerosis and hypertension. To address this, we conducted a rigorous analysis using Mendelian randomization, leveraging publicly available genetic data from

Acute Heart Failure: Measuring The Diversity Of Health Related Quality Of Life Markers

Acute Heart Failure: Measuring The Diversity Of Health Related Quality Of Life Markers Overview A recent study investigated the impact of heart failure with reduced ejection fraction (HFrEF) on the health-related quality of life (HR-QoL) of patients and the inconsistencies that may arise when using different HR-QoL measurement tools. Conducted at a

Heart Failure Polygenic Risk Predictions

Heart Failure Polygenic Risk Predictions Overview This study explores the genetic associations and risk prediction capabilities of polygenic risk scores (PRSs) derived from risk factors shared with heart failure (HF) in bi-racial populations. The risk factors considered include atrial fibrillation (AF), body mass index (BMI), coronary heart disease (CHD), systolic blood pressure

Spotlight On Heart Failure Pathophysiology: Coronary Microvascular Dysfunction