The Microbiome and Metabolism: Can Gut Flora Be the Next Endocrine Organ? Abstract The human gut microbiome has increasingly been recognized as a central determinant of metabolic health, with growing evidence suggesting that it functions not merely as a collection of commensal microorganisms but as a
Author: Nancy Ogbonna
The Death (or Rebirth) of Aspirin in Primary Prevention
The Death (or Rebirth) of Aspirin in Primary Prevention Abstract The role of aspirin in primary prevention of cardiovascular disease has undergone substantial reassessment over the past decade as emerging evidence has challenged long standing assumptions regarding its routine use in individuals without established cardiovascular disease. For many
Prehospital Stroke Scales and Mobile CT Units: Worth the Investment?
Prehospital Stroke Scales and Mobile CT Units: Worth the Investment? Abstract Rapid recognition and treatment of acute stroke remain among the most important determinants of neurological recovery and long term functional outcome. Because cerebral ischemia leads to irreversible neuronal injury within minutes, every stage of early stroke
Precision Epilepsy: How Gene-Targeted Therapies Are Changing Seizure Treatment in 2026
Precision Epilepsy How Gene-Targeted Therapies Are Changing Seizure Treatment in 2026 Key Takeaways Precision epilepsy is redefining the clinical management of seizure disorders by shifting treatment strategies from generalized symptom suppression toward interventions directed at the underlying molecular and genetic causes of disease. This transition is
Obesity as Chronic Disease: Building a Follow-up Model Like HTN/A1c
Obesity as Chronic Disease Building a Follow-up Model Like HTNA1c Abstract Obesity is increasingly recognized as a chronic, relapsing, multifactorial disease that requires long term clinical management rather than episodic intervention. Its pathophysiology involves complex interactions among genetic predisposition, neuroendocrine regulation, metabolic adaptation, environmental
From Nursing Home to Hospital and Back: Are We Finally Fixing the Revolving Door?
Pediatric Sleep Disorders: New Insights on Melatonin and Circadian Health
Pediatric Sleep Disorders New Insights on Melatonin and Circadian Health Abstract Sleep disorders in children have emerged as a significant and increasingly recognized clinical concern, with implications that extend beyond nighttime symptoms to affect physical growth, neurocognitive development, emotional regulation, and overall quality of life. Adequate
Psychedelics in Anesthesia and Pain: From OR Curiosity to Clinical Therapy
Psychedelics in Anesthesia and Pain From OR Curiosity to Clinical Therapy Abstract The integration of psychedelic substances into anesthesia and pain management represents an important and evolving development in contemporary medical practice. Historically associated with psychiatric research and later restricted due to regulatory concerns, psychedelic compounds are now reemerging
Seronegative Rheumatoid Arthritis vs Early Spondyloarthritis: Which Diagnosis Is Right?
Seronegative Rheumatoid Arthritis vs Early Spondyloarthritis Which Diagnosis Is Right Key Takeaways Differentiating seronegative rheumatoid arthritis (RA) from early spondyloarthritis (SpA) remains one of the most challenging diagnostic tasks in contemporary rheumatology. Both conditions may present with inflammatory joint symptoms in the absence of definitive serologic
Sleep as a Vital Sign: Why Internists Should Lead the Sleep Health Revolution
Sleep as a Vital Sign Why Internists Should Lead the Sleep Health Revolution Abstract Sleep medicine has undergone a significant transformation over the past two decades, evolving from a highly specialized discipline into an essential component of comprehensive primary care. Increasing recognition of sleep as a
