Bariatric Surgery In Hypertrophic Cardiomyopathy Patients Overview Existing research has hinted at a link between obesity and increased risk of acute cardiovascular events. Bariatric surgery has been shown to mitigate this risk; however, its impact on patients with both obesity and hypertrophic cardiomyopathy (HCM) remains unclear. This study aimed to assess whether
Internal Medicine
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients Overview In this retrospective cohort study utilizing IQVIA PharMetrics Plus claims data, the effectiveness of mepolizumab, a humanized anti-interleukin 5 monoclonal antibody, was explored in a real-world setting for U.S. patients with severe asthma and comorbid chronic rhinosinusitis (CRS) with or without sinus
Patellofemoral Arthroplasty Designs and Osteoarthritis Progression
Patellofemoral Arthroplasty Designs and Osteoarthritis Progression Overview This study aimed to evaluate clinical and functional outcomes, complication rates, implant survivorship, and the progression of tibiofemoral osteoarthritis (OA) in patients with isolated patellofemoral OA undergoing new inlay or onlay patellofemoral arthroplasty (PFA). The research also sought to compare different implant types and models
Music Therapy For Dementia Symptoms Treatment
Music Therapy For Dementia Symptoms Treatment Overview The study explores the impact of individualized music listening (IML) on the behavioral and psychological symptoms of dementia (BPSD), a topic previously assessed through proxy-completed questionnaires. To address methodological limitations, the researchers employed a systematic observational approach, incorporating a validated instrument, time-based sampling, and longitudinal
Transfusion-Dependent Thalassemia: Iron Overload And Organ Dysfunction
Transfusion-Dependent Thalassemia: Iron Overload And Organ Dysfunction Transfusion-dependent thalassemia (TDT) is an inherited blood disorder found most often in the Middle East and Africa. In places like Iran, beta-thalassemia, a more common type, has major and minor subtypes. The severe form, called Cooley's anemia, lacks beta protein in hemoglobin, making regular
Cognitive Behavioral Therapy: Telehealth Effectiveness For Chronic Mental Disorders
Cognitive Behavioral Therapy: Telehealth Effectiveness For Chronic Mental Disorders Overview Amidst the pandemic, the adoption of remote treatments, specifically telephone-delivered cognitive behavioral therapy (T-CBT), has witnessed a notable increase. This meta-analysis seeks to fill a gap in existing literature by evaluating the effectiveness of T-CBT in chronic and/or mental illnesses, comparing it
Gout in Patients With Inflammatory Bowel Disease
Gout in Patients with Inflammatory Bowel Disease Overview Arthritis is a well-established extra-intestinal manifestation of inflammatory bowel disease (IBD). Recent studies have indicated disruptions in uric acid metabolism among individuals with IBD. This investigation aimed to explore the link between IBD and gout using a comprehensive multi-center database (Explorys Inc.) comprising data
Acute Gout And Cardiovascular Events: Exploring the Role of Inflammation
Acute Gout And Cardiovascular Events: Exploring The Role Of Inflammation Overview In this study, the association between hospital admissions due to acute gout and major adverse cardiovascular events (MACEs) was investigated using data from the Hospital Morbidity Data Collection and Death Registrations of the Western Australian Rheumatic Disease Epidemiology Registry. The aim
Ulcerative Proctitis: Best Practice Treatment
Ulcerative Proctitis: Best Practice Treatment Ulcerative colitis (UC) is a persistent condition marked by recurrent inflammation localized to the colon. While traditionally more prevalent in industrialized nations, UC has seen increasing incidence rates in developing countries. Ulcerative proctitis (UP) is a confined form of UC, limited to the rectum, carrying a
Alcohol Consumption And The Long-Term Risk Of Mortality
Alcohol Consumption And The Long-Term Risk Of Mortality Overview This study aims to update a previous systematic review by conducting a comprehensive analysis of meta-analyses published from January 1, 2017, to March 8, 2021, to quantify sex-specific dose–response risk relationships between chronic alcohol consumption and disease occurrence and mortality. The systematic search
