BTK Inhibitors in CLL: New Clinical Evidence Reshapes First-Line Treatment

BTK Inhibitors in CLL: New Clinical Evidence Reshapes First-Line Treatment   Check back later for a possible video summary. Videos are created for most articles.     Introduction The treatment landscape for chronic lymphocytic leukemia (CLL), the most common leukemia in Western countries, has undergone a major shift with the advent of Bruton’s tyrosine kinase (BTK) inhibitors. These

VEXAS Syndrome: The Newly Discovered Disorder Every Hematologist Should Know

VEXAS Syndrome: The Newly Discovered Disorder Every Hematologist Should Know   Check back later for a possible video summary. Videos are created for most articles. Abstract This paper provides a comprehensive review of VEXAS syndrome; a newly recognized, adult-onset autoinflammatory condition with a genetic basis and complex multisystem involvement, carrying significant implications for hematologists, rheumatologists, and other specialists. First

Plasmapheresis in TTP Mimics: When Are We Getting It Wrong?

Plasmapheresis in TTP Mimics: When Are We Getting It Wrong?   Check back later for a possible video summary. Videos are created for most articles.     Introduction Plasmapheresis has revolutionized the treatment of thrombotic thrombocytopenic purpura (TTP), reducing mortality rates from nearly 100% to less than 10–20%. Despite this progress, diagnostic uncertainty remains a

Monoclonal Antibodies in Relapsed Multiple Myeloma: The Era of Bispecifics and Beyond

Monoclonal Antibodies in Relapsed Multiple Myeloma: The Era of Bispecifics and Beyond   Check back later for a possible video summary. Videos are created for most articles.   Abstract This paper provides an in-depth review of monoclonal antibody (mAb) therapies in the treatment of relapsed multiple myeloma (MM), with a particular focus on bispecific antibodies

Thrombocytopenia in the ICU: Essential Guide for Clinical Hematologists

Thrombocytopenia in the ICU: Essential Guide for Clinical Hematologists   Check back later for a possible video summary. Videos are created for most articles.     Introduction Thrombocytopenia is a frequent hematologic abnormality in critically ill patients, affecting up to 67.6% at ICU admission, with an additional 14–44% developing it during their stay. It serves as

Hidden Signs of GATA2 Deficiency: Why Doctors Miss This Rare Disorder

Hidden Signs of GATA2 Deficiency: Why Doctors Miss This Rare Disorder   Check back later for a possible video summary. Videos are created for most articles.     Introduction GATA2 deficiency is the most common hereditary predisposition to pediatric myelodysplastic syndrome (MDS), yet it remains one of the most frequently overlooked genetic disorders in clinical practice. This

Is Clonal Hematopoiesis a New Cardiovascular Risk Factor?

Is Clonal Hematopoiesis a New Cardiovascular Risk Factor? Check back later for a possible video summary. Videos are created for most articles.  Abstract This paper explores growing evidence that links clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential (CHIP), to an increased risk of

New Anticoagulants vs LMWH in Cancer-Associated Thrombosis: Latest Evidence

New Anticoagulants vs LMWH in Cancer-Associated Thrombosis: Latest Evidence Please like and subscribe if you enjoyed this video :-)   Introduction Venous thromboembolism (VTE), encompassing deep vein thrombosis and pulmonary embolism, remains one of the most common and life-threatening complications in patients with cancer.

JAK2, CALR, and MPL Mutations: Advanced Treatment Strategies That Work

JAK2, CALR, and MPL Mutations: Advanced Treatment Strategies That Work Please like and subscribe if you enjoyed this video :-)    Introduction The discovery of somatic mutations in the JAK2, CALR, and MPL genes has transformed the diagnostic and therapeutic landscape

BTK Inhibitors in CLL: New Clinical Evidence Reshapes First-Line Treatment