Cytokine Release Syndrome 2.0: Managing Immune-Effector Toxicity as Cell Therapy Moves Earlier, Broader, and Beyond CAR T

Cytokine Release Syndrome 2.0: Managing Immune-Effector Toxicity as Cell Therapy Moves Earlier, Broader, and Beyond CAR T Review Abstract Purpose: This article reviews cytokine release syndrome (CRS) and related immune-effector toxicities in the expanding era of cellular therapy, with emphasis on practical recognition, risk stratification,

Pediatric Immunology Breakthroughs: Can Tolerogenic Therapies Cure Autoimmune Disease?

Pediatric Immunology Breakthroughs: Can Tolerogenic Therapies Cure Autoimmune Disease? Review Key Takeaways Revolutionary tolerogenic therapies are transforming pediatric autoimmune disease treatment from chronic management to potential cures, offering hope for children with severe conditions. CAR T-cell therapy achieves remarkable results: 7 of 8 pediatric

Cytokine Release Syndrome 2.0: Managing Immune-Effector Toxicity as Cell Therapy Moves Earlier, Broader, and Beyond CAR T