Beyond Amyloid: New Alzheimer's Treatment Targets Alternative Brain Pathways Introduction Alzheimer's disease, the most common cause of dementia accounting for 60-70% of all cases, requires new Alzheimer's treatment approaches as current strategies show limited efficacy. According to the World Health Organization's 2022 blueprint for
Family Practice Medicine
How Diet and Exercises Prevent Dementia Through Gut-Brain Pathways
Ketogenic Diets in Neurology and Endocrinology: Friend or Fad?
Ketogenic Diets in Neurology and Endocrinology: Friend or Fad? Abstract The ketogenic diet (KD), defined by a high fat, moderate protein, and very low carbohydrate composition, has undergone a notable resurgence in both clinical practice and popular health discourse. Initially introduced in the 1920s as
Breaking Through: Latest Advances in Targeting IL-13 and IL-4 for Atopic Diseases
Hidden Link: How AFib Directly Affects Your Memory Loss Risk
Hidden Link: How AFib Directly Affects Your Memory Loss Risk Atrial fibrillation (AF) and memory loss share a concerning relationship that extends beyond coincidental occurrence. AF is the most common clinically significant arrhythmia in the world. In the United States alone, about 2.5 million people
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising?
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising? Abstract Endocrine-disrupting chemicals (EDCs) have emerged as a notable concern in reproductive health, with increasing evidence linking exposure to reduced fertility in both men and women. These compounds, which include a broad spectrum of
Autoimmunity and COVID Vaccines: Risk of Flares or Protective Benefits? A Comprehensive Analysis for Academic and Industry Experts
Autoimmunity and COVID Vaccines: Risk of Flares or Protective Benefits? A Comprehensive Analysis for Academic and Industry Experts Abstract The link between getting a COVID-19 vaccine and having an autoimmune disease is an intricate blend of immunology, public health, and clinical practice. This analytical review
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete?
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete? Abstract Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis in adults over 50 years of age and represents a major cause of morbidity, particularly when diagnosis and treatment are delayed. Traditionally, management
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures Abstract Sickle cell disease (SCD) remains one of the most pressing global health challenges, with an estimated 300,000 infants born annually with the disorder and millions more living with its lifelong complications. The burden of SCD is disproportionately higher in
When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis
When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis Introduction Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that primarily targets synovial joints, leading to progressive inflammation, cartilage destruction, and bone erosion. Traditionally, diagnosis has relied heavily on the detection of
