Alzheimer's Patients and Low Tau Burden Outcomes Overview The study focuses on individuals within the Alzheimer's Disease (AD) pathway exhibiting abnormal amyloid-beta (Aβ) and tau deposition. Specifically, it investigates a subgroup characterized by low tau levels (A+T−) and compares them to their counterparts with higher tau levels (A+T+). The research involves 397 individuals
Author: Nancy Ogbonna
Smoking And Mental Health After Lung Cancer Diagnosis
Smoking And Mental Health After Lung Cancer Diagnosis Overview This study investigated the emotional well-being, stigma experiences, and their connection to smoking history in individuals diagnosed with lung cancer. Analyzing data from 539 participants across various geographic locations from November 2019 to July 2022, the study utilized validated survey tools to assess
Multimorbidity In Patients With Cognitive Impairment And Dementia
Multimorbidity In Patients With Cognitive Impairment And Dementia Overview The study aimed to investigate the burden and clusters of multimorbidity in relation to mild cognitive impairment (MCI), dementia, and Alzheimer's disease (AD)-related plasma biomarkers among older adults. A population-based sample of 5432 participants aged 60 years and above was included, with a
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults Overview This study investigates the impact of anticholinergic (AC) medications on cognitive outcomes in autistic adults, an area that has not been extensively researched. AC medications, known for their potential to cause cognitive impairment, are commonly used for various medical and psychiatric conditions. In
NSCLC First Line Therapy Chemotherapy Combinations
NSCLC First Line Therapy Chemotherapy Combinations Overview This retrospective study explores optimal first-line treatments for non-small cell lung cancer (NSCLC) patients with brain metastases (BMs) lacking driver gene alterations. The research compares the effectiveness of immunotherapy plus chemotherapy (ICI+Chemo) against bevacizumab plus chemotherapy (Beva+Chemo). The study, conducted between March 2017 and May
Colorectal Cancer: A Nomogram To Predict Metastases
Colorectal Cancer: A Nomogram To Predict Metastases Overview This study addresses the imperative task of identifying risk factors associated with distant metastasis in early-onset colorectal cancer (EOCRC), aiming to enhance understanding of its etiology and facilitate preventive treatments. The research, utilizing data from EOCRC patients in the SEER database (2010-2015), seeks to
Tongue Tumor Staging Using Artificial Intelligence
Tongue Tumor Staging Using Artificial Intelligence Overview This study addresses the critical issue of misdiagnosis in determining the stage of tongue tumor development, which can lead to varied treatment approaches and hinder patients from receiving appropriate care. The research aims to establish an automatic recognition system for different stages of tongue tumors,
Busulfan Exposure And Malignancy Risk
Busulfan Exposure And Malignancy Risk Overview The occurrence of secondary malignancies linked to busulfan exposure is deemed low but remains insufficiently characterized. Given the rising use of this alkylating agent in pre-gene therapy conditioning for nonmalignant hematologic disorders, a more precise understanding of busulfan's potential contribution to subsequent malignancy risk is essential.
Insulin Resistance Used To Assess Malignancies In Women
Insulin Resistance Used To Assess Malignancies In Women Overview In this prospective multicenter real-world cohort study involving 571 patients diagnosed with female reproductive system malignancies, the prognostic significance of insulin resistance (IR) and systemic inflammation was investigated. The cohort, with a mean age of 52 years, predominantly comprised individuals with cervical cancer
Thromboembolism Risk In Pregnant Oncology Patients
Thromboembolism Risk In Pregnant Oncology Patients Overview This systematic review and meta-analysis investigated the incidence of venous thromboembolism (VTE) in pregnant individuals with active malignancy compared to those without malignancy. The study, based on seven cohort studies encompassing 5,928 individuals with both active malignancy and pregnancy, yielded the following key findings:
