Piclidenoson In The Treatment Of Plaque Psoriasis Overview The study focused on evaluating the effectiveness and safety of piclidenoson (CF101), an orally bioavailable agonist for the A3 adenosine receptor (A3AR), in treating moderate-to-severe plaque psoriasis. The A3AR is known to be overexpressed in the skin and peripheral blood mononuclear cells of individuals
Author: Nancy Ogbonna
Menarche Age And Risk For Adult Onset Diabetes
Menarche Age And Risk For Adult Onset Diabetes Overview This cross-sectional study explores the association between menarche age and overt diabetes in women aged 35 to 70. The research, involving 6094 participants from the Zahedan Adult Cohort Study, utilizes a questionnaire to collect demographic, fertility, anthropometric, and disease history data. Menarche age
Protein In Diet From Plant Or Animal: Cardiovascular Outcomes In Men
Protein In Diet From Plant Or Animal: Cardiovascular Outcomes In Men Overview In this cross-sectional study involving 357 elderly men, the research aimed to explore the relationship between dietary protein intake—both total and categorized as plant or animal protein—and cardiovascular outcomes and inflammatory factors. Utilizing a reliable food frequency questionnaire (FFQ) to
Hyperthyroidism Treatment And Comorbid Outcomes
Hyperthyroidism Treatment And Comorbid Outcomes Overview In this network meta-analysis, the objective was to assess the associations of different treatment modalities—anti-thyroid drugs (ATD), radioactive iodine (RAI), and thyroidectomy—with subsequent outcomes in individuals newly diagnosed with hyperthyroidism. The study conducted searches in Ovid Medline, Ovid Embase, and the Cochrane Library databases for relevant
Alzheimer’s Patients and Low Tau Burden Outcomes
Alzheimer's Patients and Low Tau Burden Outcomes Overview The study focuses on individuals within the Alzheimer's Disease (AD) pathway exhibiting abnormal amyloid-beta (Aβ) and tau deposition. Specifically, it investigates a subgroup characterized by low tau levels (A+T−) and compares them to their counterparts with higher tau levels (A+T+). The research involves 397 individuals
Smoking And Mental Health After Lung Cancer Diagnosis
Smoking And Mental Health After Lung Cancer Diagnosis Overview This study investigated the emotional well-being, stigma experiences, and their connection to smoking history in individuals diagnosed with lung cancer. Analyzing data from 539 participants across various geographic locations from November 2019 to July 2022, the study utilized validated survey tools to assess
Multimorbidity In Patients With Cognitive Impairment And Dementia
Multimorbidity In Patients With Cognitive Impairment And Dementia Overview The study aimed to investigate the burden and clusters of multimorbidity in relation to mild cognitive impairment (MCI), dementia, and Alzheimer's disease (AD)-related plasma biomarkers among older adults. A population-based sample of 5432 participants aged 60 years and above was included, with a
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults Overview This study investigates the impact of anticholinergic (AC) medications on cognitive outcomes in autistic adults, an area that has not been extensively researched. AC medications, known for their potential to cause cognitive impairment, are commonly used for various medical and psychiatric conditions. In
NSCLC First Line Therapy Chemotherapy Combinations
NSCLC First Line Therapy Chemotherapy Combinations Overview This retrospective study explores optimal first-line treatments for non-small cell lung cancer (NSCLC) patients with brain metastases (BMs) lacking driver gene alterations. The research compares the effectiveness of immunotherapy plus chemotherapy (ICI+Chemo) against bevacizumab plus chemotherapy (Beva+Chemo). The study, conducted between March 2017 and May
Colorectal Cancer: A Nomogram To Predict Metastases
Colorectal Cancer: A Nomogram To Predict Metastases Overview This study addresses the imperative task of identifying risk factors associated with distant metastasis in early-onset colorectal cancer (EOCRC), aiming to enhance understanding of its etiology and facilitate preventive treatments. The research, utilizing data from EOCRC patients in the SEER database (2010-2015), seeks to
