Off-label Medication Use In Oncology Cancer Research and Medicinal Drugs Cancer research and innovation are highly active, resulting in the introduction of new medications into the therapeutic arsenal. However, incorporating these new drugs into clinical practice is a challenging and time-consuming process due to regulatory requirements. Before a drug can be marketed and
Pediatrics
Bedside Pediatric Early Warning System: A Validation Study
Bedside Pediatric Early Warning System: A Validation Study Overview Conducted in an 80-bed pediatric oncology specialty hospital in the Netherlands, this research was initiated to evaluate the predictive utility of the adapted Bedside Pediatric Early Warning System (BedsidePEWS) score. This study aimed to explore the correlation of this score with unanticipated transfers
Eyelid Rhabdomyosarcoma Survival In Children’s Oncology
Eyelid Rhabdomyosarcoma Survival In Children's Oncology Overview Survival outcomes in Orbital Rhabdomyosarcoma (ORMS) typically show excellent results, especially in low-risk cases (stage 1, group I-III, embryonal RMS). However, long-term follow-up data on low-risk ORMS and less common subgroups treated in recent Children's Oncology Group (COG) trials were previously unreported. To fill this
Childhood Obesity: Targeted Dietary Interventions
Childhood Obesity: Targeted Dietary Interventions Childhood obesity is a global concern, and dietary interventions have shown varying effectiveness in reducing BMI in children and adolescents. However, there is little guidance on targeted dietary approaches and energy reduction, leading to inconsistent recommendations. This excellent systematic review aimed to assess the effectiveness of
What Works Best: ABA Therapy or Other Autism Treatments
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. What Works Best: ABA Therapy or Other Autism Treatments Autism Spectrum Disorder, or ASD, is a complex and manageable neurodevelopment condition that affects each child differently. For medical professionals and
Infant Formula Protein Content And Childhood Obesity
Infant Formula Protein Content And Childhood Obesity Overview Child growth and obesity risk is affected by infant feeding. In this study, we assessed the effect of protein intake in infancy on the body mass index, obesity and adiposity rebound of children aged up to 11 years. Healthy infants from five European countries
Maternal Migraines And Associated Pediatric Cancers
Maternal Migraines And Associated Pediatric Cancers Overview Maternal migraines are seen to be associated with unfavorable birth outcomes such as congenital malformations in babies, preterm births and infant low birth weight. It has been hypothesized that these unfavorable or adverse birth outcomes may be due to the intake of certain medications during
Pediatric Neuroblastoma Diagnosis Using Urinary Catecholamine Metabolites
Pediatric Neuroblastoma Diagnosis Using Urinary Catecholamine Metabolites Overview Urinary catecholamine metabolite analysis is a valuable tool in the diagnosis of neuroblastoma. There is currently no agreement with regard to the method of sampling and variable catecholamine metabolite combinations being utilized. In this study, we assessed the reliability of spot urine samples in
Pediatric Opioids And Pain Control In Fractures
Pediatric Opioids And Pain Control In Fractures Overview It has been observed over time that pediatric patients who go through a closed reduction of fractures to the forearm with standard sedation in the emergency room are given opioids around 14 times the normal amount used at discharge. It has also been observed
Pediatric Oncology: Diagnosis And Prognosis Communication
Pediatric Oncology: Diagnosis And Prognosis Communication Overview When a child is diagnosed with cancer, it is an incredibly difficult situation for everyone in the family, and the parents especially have a hard time understanding the complicated details of the diagnosis and outcome. They usually want doctors to be honest and transparent, though
