Respiratory Syncytial Virus Infection: A Tool For Assessing Clinical Severity Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infection (ARTI) and the primary reason for hospitalization among infants, leading to substantial health and socioeconomic challenges. Ranging from mild cold-like symptoms to severe lower respiratory tract infection (LRTI),
Internal Medicine
Antithyroid Drug Therapy And Cardiovascular Morbidity
Antithyroid Drug Therapy And Cardiovascular Morbidity Overview The impact of thyroid function test (TFT) variability and its link to adverse health outcomes in antithyroid drug (ATD) therapy remains an unexplored area. This study aimed to investigate the relationship between TFT variability and cardiovascular morbidity during ATD therapy. Conducted at Tampere University Hospital,
Eosinophilic Dermatosis In Hematological Malignancy (EDHM): Case Study Reports
Eosinophilic Dermatosis In Malignancy (EDHM): Case Study Reports Overview Patients with hematological malignancies may develop various skin eruptions, and one such condition is eosinophilic dermatosis of hematological malignancy (EDHM), also known as an 'insect bite-like' reaction. While cutaneous reactions are not uncommon in hematological malignancies, EDHM is a relatively rare condition that
Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness
Uterine Leiomyosarcoma: Systemic Therapy Effectiveness Overview Uterine leiomyosarcoma (uLMS) is an aggressive type of mesenchymal tumor linked to a bleak prognosis. The primary treatment for advanced uLMS is systemic chemotherapy, although the most effective regimen remains uncertain. To address this, we conducted an extensive analysis, including both meta-analysis and metaregression, aiming to
Off-label Medication Use In Oncology
Off-label Medication Use In Oncology Cancer Research and Medicinal Drugs Cancer research and innovation are highly active, resulting in the introduction of new medications into the therapeutic arsenal. However, incorporating these new drugs into clinical practice is a challenging and time-consuming process due to regulatory requirements. Before a drug can be marketed and
Chronic Hyponatremia in Acute Heart Failure
Chronic Hyponatremia in Acute Heart Failure Overview This study aimed to comprehensively assess hyponatremia in patients with acute heart failure (AHF), focusing on its prevalence, associations, hospital course, and post-discharge outcomes. The research analyzed a cohort of 8,298 AHF patients from the European Society of Cardiology Heart Failure Long-Term Registry, regardless of
Massage Therapy For Oncology Patient Pain
Massage Therapy For Oncology Patient Pain Overview This study aimed to investigate the impact of massage therapy (MT) as a nonpharmacologic approach for addressing various symptoms experienced by children, adolescents, and young adults with hematologic and/or oncologic conditions. The researchers focused on two patient groups: those with sickle cell disease (SCD) and
Eyelid Rhabdomyosarcoma Survival In Children’s Oncology
Eyelid Rhabdomyosarcoma Survival In Children's Oncology Overview Survival outcomes in Orbital Rhabdomyosarcoma (ORMS) typically show excellent results, especially in low-risk cases (stage 1, group I-III, embryonal RMS). However, long-term follow-up data on low-risk ORMS and less common subgroups treated in recent Children's Oncology Group (COG) trials were previously unreported. To fill this
Injured Athletes: A Meta-Analysis Comparing Topical And Oral Analgesic Efficacy
Injured Athletes: A Meta-Analysis Comparing Topical And Oral Analgesic Efficacy Overview Injured athletes often resort to analgesic medication for pain relief, employing both non-prescription topical and oral medications without comprehensive guidance. However, the efficacy of such pain medications in injured athletes, as compared to a placebo, has not been extensively studied. To
Sarcopenia And Chronic Kidney Disease
Sarcopenia And Chronic Kidney Disease Overview Sarcopenia and frailty are common conditions among people with chronic kidney disease (CKD), which may further enhance their risk of developing adverse health complications. Only a few studies have demonstrated the association between sarcopenia, frailty and chronic kidney disease in patients who are not on dialysis.