Hypothalamus Diversity In Anorexia Overview The study delves into the intricate relationship between the hypothalamus, hormonal regulation, and weight-related disorders, namely anorexia nervosa (AN) and obesity. Recognizing the pivotal role of the hypothalamus in maintaining energy homeostasis, the research aims to identify morphometric alterations in specific hypothalamic subregions and their associations with
Health Topics
Costs Associated With Obesity
Costs Associated With Obesity Overview The impact of obesity on mortality rates and healthcare resource utilization (HCRU) is profound, with significant variations based on demographic factors such as age, gender, and local socioeconomic status. This study aimed to assess the lifetime costs of obesity across different demographic groups and geographic areas in
Anal Fistula Patients: A Quality Of Life Tool
Anal Fistula Patients: A Quality Of Life Tool Overview The study aims to address the lack of quality of life (QoL) measurement instruments tailored specifically for patients with cryptoglandular anal fistula. Through a comprehensive approach involving qualitative patient interviews, systematic review of existing instruments, and expert input, a novel measurement instrument was
Ketamine Infusion In The Treatment Of Chronic Pain
Ketamine Infusion In The Treatment Of Chronic Pain The relentless nature of chronic pain not only causes physical discomfort but also takes a heavy emotional toll, impacting quality of life and daily functioning. Despite the widespread prevalence of chronic pain, traditional medications frequently prove inadequate in delivering sustained and satisfactory relief
Chronic Pain In Adulthood Linked To Adverse Childhood Experiences
Chronic Pain In Adulthood Linked To Adverse Childhood Experiences Overview This study aimed to elucidate the complex interplay between adverse childhood experiences (ACEs), anxiety, and chronic pain in adults through a systematic literature review (SLR) and meta-analysis. The narrative synthesis of findings revealed a substantial association between ACEs, anxiety, and chronic pain
Obesity Treated With Expandable Oral Capsules
Obesity Treated With Expandable Oral Capsules Overview This clinical trial aimed to evaluate the efficacy and safety of administering 2.24 g intragastric expandable capsules twice daily for weight management in adults with overweight or obesity. The study, conducted as a double-blind, placebo-controlled trial, enrolled 280 participants with a body mass index (BMI) ranging
First Seizure Effects on Cognition in Adults
First Seizure Effects on Cognition in Adults Overview Investigating cognitive and psychological functioning in adults after their first seizure, prior to epilepsy diagnosis and treatment, is crucial for understanding the early manifestations of neuropsychological comorbidities associated with chronic epilepsy. In this study, conducted through a telehealth-based prospective design, cognition, mood, and anxiety
Calcaneus Fractures And The Impact Of Bone Grafting On Wound Infection
Calcaneus Fractures And The Impact Of Bone Grafting On Wound Infection Overview This research aimed to assess the efficacy of bone transplantation compared to non-bone transplantation in addressing intra-articular fractures of the calcaneus and their subsequent surgical complications. Utilizing data obtained from esteemed databases such as PubMed, Embase, and Cochrane, we meticulously
Hearing Testing Using At-Home Smartphone Apps
Hearing Testing Using At-Home Smartphone Apps Over 20% of the world's population has hearing loss, with 5% facing communication challenges. This disability causes psychosocial burdens, health issues, and economic losses due to decreased productivity. Early detection and remote monitoring can help reduce these negative effects and aid clinical diagnosis and research. Pure
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis Overview This study examined the efficacy and safety of abrocitinib, a treatment for moderate-to-severe atopic dermatitis (AD), specifically focusing on patients with allergic comorbidities. Data from phase 2b and phase 3 trials were analyzed, pooling information from patients who received abrocitinib or
