Alcohol Consumption And The Long-Term Risk Of Mortality Overview This study aims to update a previous systematic review by conducting a comprehensive analysis of meta-analyses published from January 1, 2017, to March 8, 2021, to quantify sex-specific dose–response risk relationships between chronic alcohol consumption and disease occurrence and mortality. The systematic search
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Ocrelizumab Effectiveness In Multiple Sclerosis
Ocrelizumab Effectiveness In Multiple Sclerosis Overview Throughout its clinical development program, ocrelizumab has consistently demonstrated efficacy in enhancing clinical outcomes for multiple sclerosis, encompassing annualized relapse rates and confirmed disability progression. Despite these positive findings, the translation of this efficacy into real-world clinical practice remained uncertain. This study aimed to systematically compile
Pancreatitis Risk In Patients Taking Antipsychotic Medications
Pancreatitis Risk In Patients Taking Antipsychotic Medications Overview This extensive nationwide study, spanning from 2006 to 2019, investigated the potential link between antipsychotic drug use and acute pancreatitis risk. Analyzing data from 52,006 cases and 518,081 controls, the study initially suggested an increased risk associated with both first-generation and second-generation antipsychotic drugs,
Insomnia Severity And Nutrition
Insomnia Severity And Nutrition Quality sleep is essential for physical and mental well-being, with disruptions causing cognitive issues, fatigue, and even depression. When our sleep is compromised, it can have far-reaching consequences, affecting various aspects of our lives. Sleep disruptions are closely tied to cognitive issues, making it harder to think clearly
Epilepsy And The Effectiveness Of Cannabidiol Therapy
Epilepsy And The Effectiveness Of Cannabidiol Therapy There's a growing interest in the potential medical uses of cannabidiol (CBD), a non-psychoactive compound found in cannabis. CBD has been studied for its various effects, and it has shown promise in reducing seizures, particularly in children with drug-resistant epilepsy. CBD's Phase III studies showed
Gastric Xanthoma And Gastric Cancer Risk
Gastric Xanthoma And Gastric Cancer Risk Gastric cancer stands as a formidable global threat, ranking among the top cancers in incidence and mortality. Amidst known risk factors like dietary habits and infections, a lesser-known player, gastric xanthoma (GX), emerges as a potential link to this complex puzzle. This study delves into
Premature Birth And Adult Risk Of Pain and Fatigue
Premature Birth And Adult Risk Of Pain and Fatigue The Study The researchers aimed to investigate the associations between mental health, pain, and tiredness in adults born very preterm (VP; <32 weeks) or with very low birth weight (VLBW; <1500 g) and at term, as well as whether physical activity influenced these
Dermatitis And Allergies To Cosmetic Ingredients
Dermatitis And Allergies To Cosmetic Ingredients Overview In the realm of hair cosmetics, a plethora of products harbor various potent contact allergens, including additives such as preservatives. This concern is particularly pronounced among individuals involved in hairdressing, who frequently manifest hand dermatitis. Furthermore, clients and self-users, hereafter referred to as 'consumers,' may
Rheumatoid Arthritis Work Limitation Factors
Rheumatoid Arthritis Work Limitation Factors Rheumatic and musculoskeletal diseases (RMD) introduce pain and functional limitations into the workplace, affecting individuals with rheumatoid arthritis and osteoarthritis. This study delves into the multifaceted factors that shape the work challenges arising from RMD, acknowledging the broader societal costs involved. By shedding light on these
Secukinumab Therapy In Psoriasis
Secukinumab Therapy In Psoriasis Overview Psoriasis is a chronic skin condition characterized by immune-mediated inflammation, significantly affecting patients' quality of life. Secukinumab, an interleukin 17A inhibitor, has been employed as a systemic treatment for psoriasis. However, its long-term retention rates in a real-world setting in Japan have not been comprehensively studied. In
