Hepatocellular Carcinoma Treatment Outcomes: The Influence Of Butyrate Producers Overview In a retrospective multi-center study involving 747 patients with advanced hepatocellular carcinoma (HCC) treated with a combination therapy of atezolizumab and bevacizumab, the influence of butyric acid-producing enterobacteria on treatment outcomes was investigated. Previous research has established a link between the gut
Author: Nancy Ogbonna
Control of Allergic Rhinitis and Asthma Test: A COSMIN Analysis
Control of Allergic Rhinitis and Asthma Test: A COSMIN Analysis Overview The Control of Allergic Rhinitis and Asthma Test (CARAT) serves as a patient-reported outcome measurement (PROM) to evaluate the management of asthma and allergic rhinitis (AR) within a 4-week timeframe. This systematic review aimed to assess CARAT's measurement properties. Adhering to
Tislelizumab Treatment And Quality Of Life In Lung Cancer Patients
Tislelizumab Treatment And Quality Of Life In Lung Cancer Patients Overview In the Phase 3 trial RATIONALE-303 (NCT03358875), the study evaluated the health-related quality of life (HRQoL) among patients with advanced non-small cell lung cancer (NSCLC) who were treated with either tislelizumab or docetaxel. The assessment utilized three measurement instruments: EORTC QLQ-C30,
Allergic Rhinitis And Genetic Risk Factors
Allergic Rhinitis And Genetic Risk Factors Overview With the rise in atopic conditions like allergic rhinitis and the "hygiene hypothesis" in mind, numerous studies have explored whether birth order and the size of one's sibling group could act as protective factors. However, these investigations have yielded conflicting results. This study aimed to
Serum Potassium Levels And Mortality Risk in CKD
Serum Potassium Levels And Mortality Risk in CKD Overview The study delved into the impact of serum potassium levels on the health of elderly individuals with chronic kidney disease (CKD) stage 4-5. Hypokalemia and hyperkalemia were recognized as contributors to kidney function decline and sudden cardiac death. However, limited knowledge exists about
Onychomycosis And Diabetic Foot Syndrome
Onychomycosis And Diabetic Foot Syndrome Overview This systematic review aimed to investigate the prevalence of onychomycosis in individuals with diabetes and explore its connection to risk factors, particularly within the context of diabetic foot syndrome. Adhering to the PRISMA guidelines and utilizing the STROBE method, the study searched PubMed and Scopus databases
Pediatric Onychomycosis Prevalence: A Systematic Review
Pediatric Onychomycosis Prevalence: A Systematic Review Overview Onychomycosis, a prevalent nail ailment in adults, has historically been considered rare in children, despite scattered and diverse data. Recent studies, however, hint at an increasing prevalence of onychomycosis in children. This review aimed to address this issue, with two authors individually scouring PubMed, Embase,
Hormone Disturbances in Migraine Disorder: A Meta-Analysis
Hormone Disturbances in Migraine Disorder: A Meta-Analysis Overview Migraine, a prevalent cause of disability among young adults, displays a higher incidence in females and is often accompanied by stress-related disorders, hinting at a potential link with sex and stress-related hormonal mechanisms centered around the hypothalamus. Additionally, interactions with autonomic nervous system activity
IGF-1 Levels In Pediatric Low-Grade Gliomas
IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Visual Field Defects in Patients with Pituitary Tumors
Visual Field Defects in Patients with Pituitary Tumors Overview Automated perimetry is a standardized technique for assessing the visual field, commonly using the Humphrey Field Analyser (HFA) with the 24-2 or 30-2 test patterns. This study aimed to determine if the 24-2 test pattern could yield similar outcomes as the 30-2 pattern
