Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era Abstract The introduction of biologic disease modifying antirheumatic drugs has fundamentally reshaped the management of rheumatoid arthritis over the past two decades. These agents, in combination with conventional synthetic therapies and treat to target strategies, have significantly
Author: Nancy Ogbonna
Are Operating Rooms Ready for Surgical AI? New Data Reveals Critical Insights
Are Operating Rooms Ready for Surgical AI New Data Reveals Critical Insights Introduction Surgical decision making remains a critical determinant of patient outcomes, with lapses in judgment consistently identified by surgeons as the most common cause of major intraoperative errors. These judgment related failures represent
Tranexamic Acid in Non-Trauma Cases: The Hidden Risks You Should Know
Tranexamic Acid in Non-Trauma Cases The Hidden Risks You Should Know Introduction Tranexamic acid is a synthetic antifibrinolytic agent widely used to reduce bleeding by inhibiting plasminogen activation and fibrin degradation. Its efficacy in trauma related hemorrhage has led to broad acceptance across emergency
The Great Propofol Debate: Are We Too Dependent on a Single Drug?
The Great Propofol Debate Are We Too Dependent on a Single Drug Abstract Since its introduction into clinical practice in the 1980s, propofol has become a cornerstone of modern anesthesia and procedural sedation. Its rapid onset of action, short context sensitive half time, and predictable recovery profile
Silent Inflammation: The Hidden Driver of Multisystem Chronic Disease?
Silent Inflammation The Hidden Driver of Multisystem Chronic Disease Abstract Chronic low grade inflammation, often referred to as silent inflammation, is increasingly recognized as a persistent inflammatory state that occurs in the absence of the classical signs and symptoms associated with acute inflammation.
Rare Disease Diagnosis: The Promise of Whole-Genome Sequencing in Pediatrics
Rare Disease Diagnosis The Promise of Whole-Genome Sequencing in Pediatrics Abstract Rare diseases collectively affect millions of children worldwide and represent a significant source of morbidity, mortality, and long term disability. Although individual rare disorders have low prevalence, their cumulative impact places a substantial
Precision Endocrinology: How Genomic Testing Improves Thyroid Treatment Outcomes
Precision Endocrinology How Genomic Testing Improves Thyroid Treatment Outcomes Introduction Precision endocrinology represents a paradigm shift in the management of thyroid disorders, grounded in an expanding body of genetic and molecular evidence. Large scale genetic studies have demonstrated that approximately 57 to 71 percent
New Frontiers in Male Hypogonadism: Are We Over-Treating Low Testosterone?
New Frontiers in Male Hypogonadism Are We Over-Treating Low Testosterone Abstract Male hypogonadism has emerged as one of the most intensively debated topics in men’s health over the past two decades. Advances in laboratory testing, increased awareness of androgen deficiency, and widespread direct to consumer marketing have
Is Type 2 Diabetes Reversible? New Research Challenges Medical Consensus
Is Type 2 Diabetes Reversible? New Research Challenges Medical Consensus Introduction The concept of type 2 diabetes reversibility represents a profound shift in the understanding and management of a condition long regarded as chronic and progressive. Diabetes remains a major global health burden, with prevalence
Long COVID and the Brain: Decoding Post-Viral Neuroinflammation
Long COVID and the Brain: Decoding Post-Viral Neuroinflammation Abstract Long COVID has emerged as a significant and evolving global health challenge, affecting millions of individuals following acute infection with SARS-CoV-2. While respiratory and systemic symptoms were initially the primary focus of clinical attention, it has
