The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy? Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity. By simultaneously targeting
Author: Nancy Ogbonna
Why Tau Antibody Trials Failed in Alzheimer’s: New Evidence Reveals Critical Gaps
Why Tau Antibody Trials Failed in Alzheimer’s New Evidence Reveals Critical Gaps Introduction Tau directed antibody therapies represent one of the most scientifically compelling yet clinically challenging areas in the treatment of Alzheimer’s disease. Alzheimer’s disease is a progressive neurodegenerative disorder whose prevalence doubles approximately
The Silent Threat: Awareness Under Anesthesia in the Age of Light Sedation
The Silent Threat Awareness Under Anesthesia in the Age of Light Sedation Abstract Purpose This paper examines the phenomenon of awareness under anesthesia, with particular emphasis on its increased risk in the contemporary use of light anesthesia and sedation techniques. As anesthetic practice evolves toward lower drug
Skyrocketing Cancer Drug Prices: Can Oncologists Influence Policy?
Skyrocketing Cancer Drug Prices Can Oncologists Influence Policy Abstract The rapid escalation of cancer drug prices has emerged as a major challenge in contemporary oncology practice, with many newly approved therapies carrying annual costs that exceed one hundred thousand dollars per patient. This
The “Code Sepsis” Fatigue: When Protocols Collide with Clinical Judgment
The “Code Sepsis” Fatigue: When Protocols Collide with Clinical Judgment Abstract The global adoption of standardized sepsis protocols has been a central strategy in improving outcomes for patients with suspected or confirmed sepsis. Initiatives such as early warning systems, sepsis bundles, and time based
The Endocrine Disruptor Epidemic: What Should Clinicians Be Telling Patients?
The Endocrine Disruptor Epidemic: What Should Clinicians Be Telling Patients? Abstract Endocrine disrupting chemicals represent a growing public health concern that requires heightened awareness and engagement from healthcare professionals across disciplines. These substances, which include both synthetic and naturally occurring compounds, have the capacity
Preeclampsia Prediction and Prevention: Are We Entering a New Era?
Preeclampsia Prediction and Prevention Are We Entering a New Era Abstract Preeclampsia remains a major contributor to maternal and perinatal morbidity and mortality worldwide, affecting an estimated 2 to 8 percent of pregnancies. Despite advances in obstetric care, the condition continues to pose significant challenges
Uterine Transplant Success Rates: Breakthrough Data from 2025 Clinical Trials
Uterine Transplant Success Rates Breakthrough Data from 2025 Clinical Trials Introduction Uterine transplantation has emerged as a transformative therapeutic option for women with uterine factor infertility, a condition that affects approximately five percent of women of reproductive age worldwide. Uterine factor infertility is defined
Digital Phenotyping in Psychiatry: What Clinical Evidence Reveals in 2025
Direct-to-Consumer Lab Testing: Help or Hindrance for Internists?
Direct-to-Consumer Lab Testing: Help or Hindrance for Internists? Check out our extensive video library (see channel for our latest videos) Abstract Direct-to-consumer laboratory testing has become an increasingly prominent feature of modern healthcare, offering patients the ability to independently order diagnostic tests without the
