From Skin to Gut: Unraveling the Immunopathogenesis of Eosinophilic Esophagitis Abstract Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease of the esophagus [1] that has become a paradigmatic model for understanding the interconnected skin–gut axis in allergic disease. Once considered a rare disorder, EoE has rapidly emerged
Author: Nancy Ogbonna
The Hidden Link Between Psoriasis and Crohn’s: Essential Insights for Clinical Practice
The Hidden Link Between Psoriasis and Crohn’s: Essential Insights for Clinical Practice Introduction Psoriasis and Crohn’s disease share a complex and clinically notable relationship that extends well beyond coincidental comorbidity. Psoriasis, a chronic immune-mediated skin condition, affects an estimated 2% to 3% of the global population,
Continuous Glucose Monitoring (CGM) for Type 2 Diabetes: Should It Be the Standard?
GLP-1 Agonists for NASH Treatment: New Clinical Evidence Reveals Surprising Results
Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025
Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025 Introduction Subclinical Cushing’s syndrome (SCS) presents a striking diagnostic paradox. While the classic form of Cushing’s syndrome is rare, with an estimated prevalence of approximately 1 case per 100,000 individuals, subclinical Cushing’s
The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review
The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review Abstract Background:Chronic kidney disease (CKD) affects more than 10% of the global population and is increasingly recognized as a critical public health challenge. Its rising prevalence is largely attributed to
Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment?
Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment? Abstract Background and Purpose:The global incidence of thyroid cancer has risen sharply over the past three decades. Data indicate that annual incidence increased from 5.0 cases per 100,000 individuals in 1975 to 14.6 cases per
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising?
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising? Abstract Endocrine-disrupting chemicals (EDCs) have emerged as a notable concern in reproductive health, with increasing evidence linking exposure to reduced fertility in both men and women. These compounds, which include a broad spectrum of
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete?
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete? Abstract Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis in adults over 50 years of age and represents a major cause of morbidity, particularly when diagnosis and treatment are delayed. Traditionally, management
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures Abstract Sickle cell disease (SCD) remains one of the most pressing global health challenges, with an estimated 300,000 infants born annually with the disorder and millions more living with its lifelong complications. The burden of SCD is disproportionately higher in
