Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness

Uterine Leiomyosarcoma: Systemic Therapy Effectiveness Overview Uterine leiomyosarcoma (uLMS) is an aggressive type of mesenchymal tumor linked to a bleak prognosis. The primary treatment for advanced uLMS is systemic chemotherapy, although the most effective regimen remains uncertain. To address this, we conducted an extensive analysis, including both meta-analysis and metaregression, aiming to

Chronic Hyponatremia in Acute Heart Failure

Chronic Hyponatremia in Acute Heart Failure Overview This study aimed to comprehensively assess hyponatremia in patients with acute heart failure (AHF), focusing on its prevalence, associations, hospital course, and post-discharge outcomes. The research analyzed a cohort of 8,298 AHF patients from the European Society of Cardiology Heart Failure Long-Term Registry, regardless of

Massage Therapy For Oncology Patient Pain

Massage Therapy For Oncology Patient Pain Overview This study aimed to investigate the impact of massage therapy (MT) as a nonpharmacologic approach for addressing various symptoms experienced by children, adolescents, and young adults with hematologic and/or oncologic conditions. The researchers focused on two patient groups: those with sickle cell disease (SCD) and

Eyelid Rhabdomyosarcoma Survival In Children’s Oncology

Eyelid Rhabdomyosarcoma Survival In Children's Oncology Overview Survival outcomes in Orbital Rhabdomyosarcoma (ORMS) typically show excellent results, especially in low-risk cases (stage 1, group I-III, embryonal RMS). However, long-term follow-up data on low-risk ORMS and less common subgroups treated in recent Children's Oncology Group (COG) trials were previously unreported. To fill this

Injured Athletes: A Meta-Analysis Comparing Topical And Oral Analgesic Efficacy

Injured Athletes: A Meta-Analysis Comparing Topical And Oral Analgesic Efficacy Overview Injured athletes often resort to analgesic medication for pain relief, employing both non-prescription topical and oral medications without comprehensive guidance. However, the efficacy of such pain medications in injured athletes, as compared to a placebo, has not been extensively studied. To

Sarcopenia And Chronic Kidney Disease

Sarcopenia And Chronic Kidney Disease Overview Sarcopenia and frailty are common conditions among people with chronic kidney disease (CKD), which may further enhance their risk of developing adverse health complications. Only a few studies have demonstrated the association between sarcopenia, frailty and chronic kidney disease in patients who are not on dialysis.

Diabetic Peripheral Neuropathy Diagnosis Using Nerve Ultrasonography

Diabetic Peripheral Neuropathy Diagnosis Using Nerve Ultrasonography Overview The conventional diagnostic modality for diabetic peripheral neuropathy is via the use of nerve conduction studies (NCS), however, this investigation does not evaluate or demonstrate the structure of the nerve. This research was aimed at investigating the use of peripheral nerve ultrasonography as a

Renal Transplant Risks With Prostate Cancer

Renal Transplant Risks With Prostate Cancer Overview Renal transplant candidates are recommended to undergo a systematic screening for prostate cancer at the time of listing. It is a growing concern that low-risk prostate cancer diagnosis may lead to reduced access to renal transplant services without any significant oncological benefit. The aim of this

Urothelial Carcinoma – Ureteral and Renal Pelvic Tumors

Urothelial Carcinoma - Ureteral and Renal Pelvic Tumors Overview Ureteropelvic and renal pelvic carcinoma have similar origins, however, variations in genetic and clinical parameters makes them two distinct conditions. The single-center data obtained for the molecular subtypes and characteristics of the two muscle-invasive tumors were validated using clinical data from the Surveillance,

Merkel Cell Carcinoma: A Case Of Metastasis to the Tonsils

Merkel Cell Carcinoma: A Case Of Metastasis to the Tonsils Overview Tonsillar metastases of Merkel cell carcinoma (MCC) are very rare. There are as few as five documented and published cases. In this report, we present a case of palatine tonsillar Merkel cell carcinoma metastases in a patient who did not show

Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness