Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete?

Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete? Abstract Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis in adults over 50 years of age and represents a major cause of morbidity, particularly when diagnosis and treatment are delayed. Traditionally, management

New Frontiers in Sickle Cell Disease: CRISPR-Based Cures

New Frontiers in Sickle Cell Disease: CRISPR-Based Cures Abstract Sickle cell disease (SCD) remains one of the most pressing global health challenges, with an estimated 300,000 infants born annually with the disorder and millions more living with its lifelong complications. The burden of SCD is disproportionately higher in

When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis

When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis Introduction Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that primarily targets synovial joints, leading to progressive inflammation, cartilage destruction, and bone erosion. Traditionally, diagnosis has relied heavily on the detection of

Venetoclax-based Regimens in AML: The New Standard or a Temporary Fix?

Venetoclax-based Regimens in AML: The New Standard or a Temporary Fix? Abstract Acute myeloid leukemia (AML) remains a challenging hematologic malignancy, particularly among older adults and patients unfit for intensive chemotherapy. Over the past decade, treatment models have shifted with the advent of venetoclax, a selective BCL-2 inhibitor,

Testosterone Replacement Therapy: New Guidelines Challenge Old Beliefs

Testosterone Replacement Therapy: New Guidelines Challenge Old Beliefs Introduction Testosterone replacement therapy (TRT) usage has risen sharply over the past two decades, with rates tripling across the United States. By 2013, an estimated 2.3 million American men were receiving this treatment, reflecting both

The Preventive Medicine Dilemma: How to Keep Patients Healthy in 15 Minutes or Less

The Preventive Medicine Dilemma: How to Keep Patients Healthy in 15 Minutes or Less   Abstract The modern healthcare system faces an urgent challenge: delivering high-quality preventive care within increasingly limited time frames. Evidence shows that the median primary care visit lasts just 15.7

The Truth About Vitamins: What Nutritional Supplement Research Actually Shows in 2025

The Truth About Vitamins: What Nutritional Supplement Research Actually Shows in 2025 Check back later for a possible video summary.   Introduction Nutritional supplement use is widespread in the United States, yet a growing body of research reveals a notable gap between

The “Pre-Pre-Diabetes” Zone: Are We Overdiagnosing Glycemic Risk?

The “Pre-Pre-Diabetes” Zone: Are We Overdiagnosing Glycemic Risk? Check back later for a possible video summary. Abstract Recent advancements in the understanding of glycemic dysregulation have led to more sensitive criteria for diagnosing prediabetes. As a result, growing concern has emerged regarding

Reevaluating the Annual ECG: Screening Tool or Waste of Resources?

Reevaluating the Annual ECG: Screening Tool or Waste of Resources? Check back later for a possible video summary. Videos are created for most articles. Abstract The routine use of electrocardiogram (ECG) screening remains a topic of ongoing debate in modern healthcare. Questions

Early Intervention Autism: New Research Shows 87% Success Rate at 18 Months

Early Intervention Autism: New Research Shows 87% Success Rate at 18 Months Check back later for a possible video summary. Videos are created for most articles.   Introduction Early intervention strategies for Autism Spectrum Disorder (ASD) have gained increasing importance as global prevalence

Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete?