nusinersen therapy for pediatric spinal muscular atrophy Study Background Spinal muscular atrophy (SMA) is an inherited motor neuron disease caused by the degeneration of anterior horn cells of the spinal cord and brainstem. SMA primarily affects babies and young children and has an incidence of 1:10,000. It is caused by a homozygous
Neurology
Remission of Renal Cell Carcinoma With Brain Metastases: A Case Study
Remission of Renal Cell Carcinoma With Brain Metastases: A Case Study Cases of complete remission of cancers with brain metastases are very rare. It’s often brought by tyrosine kinase inhibitor monotherapy in patients with metastatic renal cell carcinoma. For metastatic renal cell carcinoma (mRCC) patients, the case of brain metastasis has been
Cochlear Implants and Vestibular Screening
Cochlear Implants and Vestibular Screening The Study Vestibular dysfunction is one of the many risks of placing a cochlear implant (CI). However, the use of the physical exam to screen CI candidates for vestibular dysfunction is not studied enough. The study’s goal is to explore the preoperative role of the clinical head
Lung Cancer with Brain Metastasis After Late-Onset Bipolar Disorder: A Case Report
Lung Cancer with Brain Metastasis After Late-Onset Bipolar Disorder: A Case Report Background Bipolar disorder is a multifactorial illness with uncertain etiology and geriatric new-onset manic episodes are highly associated with secondary organic causes. The presented case demonstrates the importance of excluding secondary causes during the entire disease course. Overview Bipolar disorder is a
LEAP-MS: Adaptions for Advanced Stages
LEAP-MS: Adaptions for Advanced Stages Lifestyle, Exercise and Activity Package for People Living with Progressive Multiple Sclerosis (LEAP-MS): adaptations for remote delivery & improved efficiency Multiple sclerosis (MS) is the most common neurologic disorder of young and middle-aged adults. MS expresses itself in four clinical forms: relapsing-remitting MS (RRMS), secondary progressive MS
MS: Exercise Impacts on MRI
MS: Exercise Impacts on MRI Multiple sclerosis (MS) is a chronic condition that affects the optic nerves, spinal cord, and brain. Symptoms of MS include body tingling, numbness, weakness, and poor vision. Other uncommon symptoms include cognitive problems, urinary issues, and muscle stiffness. The problem with most cases of MS is it's
Extrapontine Myelinolysis and Pituitary Tumor Apoplexy in Pregnancy
Extrapontine Myelinolysis and Pituitary Tumor Apoplexy in Pregnancy Background Pituitary tumor apoplexy (PTA) is an uncommon but potentially fatal clinical emergency resulting from abrupt ischemic infarction or hemorrhage of the pituitary tumor. A variety of precipitating factors has been linked to PTA, including pregnancy. However, gestational pituitary apoplexy is limited to isolated
Stroke in the Presence of Renal Disease
Can Sotagliflozin Prevent Cardiovascular Ailments for Patients with Diabetes and Chronic Kidney Disease?
Can Sotagliflozin Prevent Cardiovascular Ailments for Patients with Diabetes and Chronic Kidney Disease Cardiovascular diseases, including stroke, are major healthcare issues affecting humans worldwide. Between 2010 and 2030, the estimated total medical costs might escalate to from $273–$818 billion in the United States alone. Modifiable risk factors for stroke include hypertension, diabetes,
