Obesity Treatment With Tirzepatide And Semaglutide Overview The aim of this study was to compare the effectiveness of obesity treatment with tirzepatide at doses of 10 mg and 15 mg with semaglutide at a dose of 2.4. The comparison was conducted using an indirect treatment comparison method. The study utilized data from the
Endocrinology
Bipolar Disorder And The Impact Of Insulin Sensitivity
Bipolar Disorder And The Impact Of Insulin Sensitivity Overview This study investigated the impact of insulin resistance (IR) and insulin sensitivity on various brain parameters in individuals with bipolar disorder (BD). Bipolar disorder is associated with structural and functional brain changes, and BD patients have an increased risk of developing insulin resistance,
Insulin Therapy for Wound Healing: A Meta-Analysis
Insulin Therapy for Wound Healing: A Meta-Analysis Overview Insulin, known for its affordability and widespread availability, has emerged as a promising agent in the realm of wound healing. This study delved into the potential of local insulin administration to facilitate the recovery of damaged skin among non-diabetic adults. To achieve this, a
Endocrine Therapy Outcomes In Senior Breast Cancer Patients
Endocrine Therapy Outcomes In Senior Breast Cancer Patients Overview This study investigated the management of early-stage, hormone receptor-positive, and human epidermal growth factor receptor 2 negative (HR+/HER2−) breast cancer in older women aged 70 to 90 years between 2010 and 2015. Specifically, it focused on patients who underwent lumpectomy and omitted radiation
Postoperative Delirium In The NICU: Hormonal Risk Factors
Postoperative Delirium In The NICU: Hormonal Risk Factors In neurosurgery, pituitary adenoma ranks as the second most common brain tumor. Recent advances in endoscope-assisted transsphenoidal surgery have revolutionized tumor resection, reducing complications. However, postoperative complications, particularly endocrine-related issues, remain critical in neurosurgical intensive care units (NICUs). Notably, postoperative delirium, intricately linked
Onychomycosis And Diabetic Foot Syndrome
Onychomycosis And Diabetic Foot Syndrome Overview This systematic review aimed to investigate the prevalence of onychomycosis in individuals with diabetes and explore its connection to risk factors, particularly within the context of diabetic foot syndrome. Adhering to the PRISMA guidelines and utilizing the STROBE method, the study searched PubMed and Scopus databases
Hormone Disturbances in Migraine Disorder: A Meta-Analysis
Hormone Disturbances in Migraine Disorder: A Meta-Analysis Overview Migraine, a prevalent cause of disability among young adults, displays a higher incidence in females and is often accompanied by stress-related disorders, hinting at a potential link with sex and stress-related hormonal mechanisms centered around the hypothalamus. Additionally, interactions with autonomic nervous system activity
IGF-1 Levels In Pediatric Low-Grade Gliomas
IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Visual Field Defects in Patients with Pituitary Tumors
Visual Field Defects in Patients with Pituitary Tumors Overview Automated perimetry is a standardized technique for assessing the visual field, commonly using the Humphrey Field Analyser (HFA) with the 24-2 or 30-2 test patterns. This study aimed to determine if the 24-2 test pattern could yield similar outcomes as the 30-2 pattern
Levothyroxine Treatment In Patients With Thyroid Cancer
Levothyroxine Treatment In Patients With Thyroid Cancer The quest to establish effective therapy for hypothyroid obese patients remains ongoing, largely due to the challenge posed by thyrotropin-stimulating hormone (TSH) levels as a dependable marker of euthyroidism compared to nonobese patients. The positive correlation between TSH levels and body mass index (BMI)