Allergic Rhinitis And Genetic Risk Factors Overview With the rise in atopic conditions like allergic rhinitis and the "hygiene hypothesis" in mind, numerous studies have explored whether birth order and the size of one's sibling group could act as protective factors. However, these investigations have yielded conflicting results. This study aimed to
Pediatrics
Childhood BMI and Allergies: A Comprehensive Review
Childhood BMI and Allergies: A Comprehensive Review Allergic conditions such as asthma, eczema, allergic rhinitis, and food allergies are prevalent chronic ailments that affect both children and adults. They pose a range of challenges including psychological stress, disrupted sleep, reduced work productivity, and increased healthcare expenses. Researchers have over time pinpointed
Pediatric Onychomycosis Prevalence: A Systematic Review
Pediatric Onychomycosis Prevalence: A Systematic Review Overview Onychomycosis, a prevalent nail ailment in adults, has historically been considered rare in children, despite scattered and diverse data. Recent studies, however, hint at an increasing prevalence of onychomycosis in children. This review aimed to address this issue, with two authors individually scouring PubMed, Embase,
IGF-1 Levels In Pediatric Low-Grade Gliomas
IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Chronic Spontaneous Urticaria: Studying Age-Specific Therapies
Chronic Spontaneous Urticaria: Studying Age-Specific Therapies Overview Chronic spontaneous urticaria (CSU) presents differently in pediatric and adult populations. A retrospective analysis of 751 CSU patients (162 pediatrics and 589 adults) revealed shorter disease duration and lower angioedema rates in pediatric cases. Adults showed higher prevalence of anti-thyroid peroxidase positivity, elevated CRP, eosinopenia,
Ocular Surgery In Infants And Post-Op Eye Drop Risks
Ocular Surgery In Infants And Post-Op Eye Drop Risks Overview This clinical observational cohort study delves into the prevalence and risk factors associated with hypothalamus-pituitary-adrenal (HPA) axis suppression in infants subjected to glucocorticoid (GC) eye drops subsequent to ocular surgery, focusing on cataract and glaucoma procedures. The research aims to discern the
Respiratory Syncytial Virus Infection: A Tool For Assessing Clinical Severity
Respiratory Syncytial Virus Infection: A Tool For Assessing Clinical Severity Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infection (ARTI) and the primary reason for hospitalization among infants, leading to substantial health and socioeconomic challenges. Ranging from mild cold-like symptoms to severe lower respiratory tract infection (LRTI),
Off-label Medication Use In Oncology
Off-label Medication Use In Oncology Cancer Research and Medicinal Drugs Cancer research and innovation are highly active, resulting in the introduction of new medications into the therapeutic arsenal. However, incorporating these new drugs into clinical practice is a challenging and time-consuming process due to regulatory requirements. Before a drug can be marketed and
Bedside Pediatric Early Warning System: A Validation Study
Bedside Pediatric Early Warning System: A Validation Study Overview Conducted in an 80-bed pediatric oncology specialty hospital in the Netherlands, this research was initiated to evaluate the predictive utility of the adapted Bedside Pediatric Early Warning System (BedsidePEWS) score. This study aimed to explore the correlation of this score with unanticipated transfers
Eyelid Rhabdomyosarcoma Survival In Children’s Oncology
Eyelid Rhabdomyosarcoma Survival In Children's Oncology Overview Survival outcomes in Orbital Rhabdomyosarcoma (ORMS) typically show excellent results, especially in low-risk cases (stage 1, group I-III, embryonal RMS). However, long-term follow-up data on low-risk ORMS and less common subgroups treated in recent Children's Oncology Group (COG) trials were previously unreported. To fill this
