NSCLC First Line Therapy Chemotherapy Combinations Overview This retrospective study explores optimal first-line treatments for non-small cell lung cancer (NSCLC) patients with brain metastases (BMs) lacking driver gene alterations. The research compares the effectiveness of immunotherapy plus chemotherapy (ICI+Chemo) against bevacizumab plus chemotherapy (Beva+Chemo). The study, conducted between March 2017 and May
Oncology
Colorectal Cancer: A Nomogram To Predict Metastases
Colorectal Cancer: A Nomogram To Predict Metastases Overview This study addresses the imperative task of identifying risk factors associated with distant metastasis in early-onset colorectal cancer (EOCRC), aiming to enhance understanding of its etiology and facilitate preventive treatments. The research, utilizing data from EOCRC patients in the SEER database (2010-2015), seeks to
Tongue Tumor Staging Using Artificial Intelligence
Tongue Tumor Staging Using Artificial Intelligence Overview This study addresses the critical issue of misdiagnosis in determining the stage of tongue tumor development, which can lead to varied treatment approaches and hinder patients from receiving appropriate care. The research aims to establish an automatic recognition system for different stages of tongue tumors,
Busulfan Exposure And Malignancy Risk
Busulfan Exposure And Malignancy Risk Overview The occurrence of secondary malignancies linked to busulfan exposure is deemed low but remains insufficiently characterized. Given the rising use of this alkylating agent in pre-gene therapy conditioning for nonmalignant hematologic disorders, a more precise understanding of busulfan's potential contribution to subsequent malignancy risk is essential.
Insulin Resistance Used To Assess Malignancies In Women
Insulin Resistance Used To Assess Malignancies In Women Overview In this prospective multicenter real-world cohort study involving 571 patients diagnosed with female reproductive system malignancies, the prognostic significance of insulin resistance (IR) and systemic inflammation was investigated. The cohort, with a mean age of 52 years, predominantly comprised individuals with cervical cancer
Thromboembolism Risk In Pregnant Oncology Patients
Thromboembolism Risk In Pregnant Oncology Patients Overview This systematic review and meta-analysis investigated the incidence of venous thromboembolism (VTE) in pregnant individuals with active malignancy compared to those without malignancy. The study, based on seven cohort studies encompassing 5,928 individuals with both active malignancy and pregnancy, yielded the following key findings:
Testicular Cancer And Psychological Distress
Testicular Cancer And Psychological Distress In 2020, testicular cancer (TC) affected 74,458 men, representing 0.4% of global cancer cases. Predominant among young men of European descent, TC's primary treatment involves orchiectomy, boasting a substantial 95% 5-year survival rate. However, the aftermath includes enduring psychological distress, with 20% of men grappling with emotional
Fistula Presence As A Cancer Risk Factor In Crohn’s Disease
Fistula Presence As A Cancer Risk Factor In Crohn's Disease Overview In this retrospective cohort study, the researchers aimed to delve into the cancer risk among patients with Crohn's disease (CD) based on the presence or absence of perianal fistulas (PF). The study spanned from January 1, 2013, to December 31, 2014,
Gastric Xanthoma And Gastric Cancer Risk
Gastric Xanthoma And Gastric Cancer Risk Gastric cancer stands as a formidable global threat, ranking among the top cancers in incidence and mortality. Amidst known risk factors like dietary habits and infections, a lesser-known player, gastric xanthoma (GX), emerges as a potential link to this complex puzzle. This study delves into
Spontaneous Bladder Rupture In Bladder Cancer Patients
Spontaneous Bladder Rupture In Bladder Cancer Patients Spontaneous rupture of the urinary bladder is an uncommon yet severe condition in which the bladder wall tears, occurring without any associated trauma or instrumentation. This means that the bladder, without any external force or medical procedure, experiences a tear or perforation. The rarity
