Sleep as a Vital Sign: Why Internists Should Lead the Sleep Health Revolution

Sleep as a Vital Sign Why Internists Should Lead the Sleep Health Revolution   Abstract Sleep medicine has undergone a significant transformation over the past two decades, evolving from a highly specialized discipline into an essential component of comprehensive primary care. Increasing recognition of sleep as a

Predicting Rheumatoid Arthritis Treatment Success: New Biomarker Breakthrough

Predicting Rheumatoid Arthritis Treatment Success New Biomarker Breakthrough   Key Takeaways Rheumatoid arthritis is a chronic systemic autoimmune disease affecting approximately 1 percent of the global population. Despite major advances in biologic and targeted synthetic disease modifying antirheumatic drugs, treatment success remains highly variable. Approximately

Food Allergy Desensitization: Is Oral Immunotherapy Ready for Prime Time?

Food Allergy Desensitization: Is Oral Immunotherapy Ready for Prime Time?   Abstract Food allergies affect millions of people worldwide and can cause severe, life-threatening reactions. Traditional management has focused on strict food avoidance and emergency treatment. Oral immunotherapy (OIT) has emerged as a promising treatment

AI in Internal Medicine: Can Algorithms Outperform the Clinical Intuition of Experienced Physicians?

AI in Internal Medicine: Can Algorithms Outperform the Clinical Intuition of Experienced Physicians?   Abstract This paper examines the growing role of artificial intelligence in internal medicine and addresses the critical question of whether algorithmic approaches can surpass the clinical intuition developed by experienced physicians

The Decline of Physical Examination Skills in Internal Medicine: An Existential Threat?

The Decline of Physical Examination Skills in Internal Medicine An Existential Threat   Abstract The physical examination has historically served as a central pillar of medical practice, guiding diagnostic reasoning, informing clinical decision making, and fostering meaningful physician patient relationships. For generations, proficiency in bedside examination has

Beyond Thresholds: Why Continuous Risk Assessment Improves Hypertension Treatment

Beyond Thresholds: Why Continuous Risk Assessment Improves Hypertension Treatment Introduction Hypertension treatment based solely on blood pressure thresholds may miss critical opportunities to prevent cardiovascular disease. For decades, physicians have relied on the 140/90 mm Hg cutoff to determine which patients require pharmacological

Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era?

Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era   Abstract The introduction of biologic disease modifying antirheumatic drugs has fundamentally reshaped the management of rheumatoid arthritis over the past two decades. These agents, in combination with conventional synthetic therapies and treat to target strategies, have significantly

Metformin in 2025: Still the King or Time to Step Aside?

Metformin in 2025: Still the King or Time to Step Aside?   Abstract Metformin has reigned as the first-line therapeutic option for type 2 diabetes mellitus for over six decades, earning its moniker as the “king” of anti-diabetic medications. As we advance through 2025, the diabetes

Epigenetics and Brain Plasticity: Can We Rewrite the Neurological Code?

Epigenetics and Brain Plasticity: Can We Rewrite the Neurological Code?   Introduction More than half of children are estimated to experience at least one form of early-life stress, contributing to 30–40% of all mood, drug, and psychiatric disorders. Neural plasticity, a remarkable characteristic of

Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron

Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron   Abstract Anemia of chronic disease (ACD) represents the second most common form of anemia worldwide, affecting millions of patients with underlying inflammatory conditions. Traditionally understood as a disorder primarily involving disruption of iron metabolism, recent

Sleep as a Vital Sign: Why Internists Should Lead the Sleep Health Revolution