Bipolar Disorder And The Impact Of Insulin Sensitivity Overview This study investigated the impact of insulin resistance (IR) and insulin sensitivity on various brain parameters in individuals with bipolar disorder (BD). Bipolar disorder is associated with structural and functional brain changes, and BD patients have an increased risk of developing insulin resistance,
Internal Medicine
Blue Light Therapy For Melasma Patients
Blue Light Therapy For Melasma Patients Melasma, a common skin pigmentation condition, presents as distinctive brown spots on the face, notably affecting individuals with darker skin tones. Although the exact causes remain elusive, factors such as solar radiation, genetics, and hormonal fluctuations are believed to play pivotal roles. Solar radiation, including
Insulin Therapy for Wound Healing: A Meta-Analysis
Insulin Therapy for Wound Healing: A Meta-Analysis Overview Insulin, known for its affordability and widespread availability, has emerged as a promising agent in the realm of wound healing. This study delved into the potential of local insulin administration to facilitate the recovery of damaged skin among non-diabetic adults. To achieve this, a
Cabozantinib Therapy In Hepatocellular Carcinoma
Cabozantinib Therapy In Hepatocellular Carcinoma Hepatocellular carcinoma (HCC) is a predominant form of liver cancer, accounting for approximately 90% of cases. Unfortunately, it carries a grim prognosis, with a median survival rate ranging from 6 to 18 months. Historically, sorafenib had been the established first-line therapy for HCC. However, in recent
Obese Children And Related Skin Conditions
Obese Children And Related Skin Conditions The World Health Organization defines overweight and obesity based on the body mass index (BMI), which is calculated as weight (kg) divided by height (m2). When assessing overweight and obesity in children, it's important to consider their age and gender. To do this, percentile curves
PD-1/L1 Inhibitors: Treatment Efficacy In Urothelial Carcinoma
PD-1/L1 Inhibitors: Treatment Efficacy In Urothelial Carcinoma Overview Programmed cell death‐1/ligand 1 (PD-1/PD-L1) inhibitors represent a novel therapeutic approach for advanced urothelial carcinoma, prompting the need for a comparative assessment of their effectiveness and safety in comparison to traditional chemotherapy. To address this, a comprehensive meta-analysis of randomized controlled trials conducted until
Encapsulated Papillary Carcinoma Membrane Characteristics
Encapsulated Papillary Carcinoma Membrane Characteristics Overview This study focused on encapsulated papillary carcinoma (EPC), a type of breast carcinoma characterized by a thick fibrous capsule-like structure surrounding the tumor, often interpreted as a thickened basement membrane (BM). The primary objective was to investigate the geometric properties of the EPC capsule and determine
Ibrutinib Treatment In Waldenström Macroglobulinemia
Ibrutinib Treatment In Waldenström Macroglobulinemia Waldenström macroglobulinemia (WM) is a rare type of non-hogdkins lymphoma driven by the gene mutation MYD88L265P. Ibrutinib, the first approved treatment, is effective but can cause side effects. A study found that 27% of WM patients needed to reduce Ibrutinib doses due to side effects like
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence Overview Eyelid sebaceous gland carcinoma (SGC) is a highly malignant condition with a significant recurrence risk. This study aimed to create a predictive nomogram for SGC recurrence based on risk factors. A retrospective study involving 391 patients from one hospital (304) and grassroots hospitals (87)
Stomach Cancer: A Meta-Analysis Of Robotic Surgery Complications
Stomach Cancer: A Meta-Analysis Of Robotic Surgery Complications Gastric or stomach cancer prevalence varies significantly around the world, with higher rates in Asia, Africa, South America, and Eastern Europe. However, in the United States, stomach cancer is a growing concern due to its increased occurrence in the elderly population and its
