Hidden Links: How Gut Microbiome Triggers Chronic Inflammation in Disease Introduction The gut microbiome and inflammation share intricate connections that profoundly impact human health. Often called the “forgotten organ,” the gut microbiota plays critical roles in training and developing major components of the
Gastroenterology
From Skin to Gut: Unraveling the Immunopathogenesis of Eosinophilic Esophagitis
From Skin to Gut: Unraveling the Immunopathogenesis of Eosinophilic Esophagitis Abstract Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease of the esophagus [1] that has become a paradigmatic model for understanding the interconnected skin–gut axis in allergic disease. Once considered a rare disorder, EoE has rapidly emerged
The Hidden Link Between Psoriasis and Crohn’s: Essential Insights for Clinical Practice
The Hidden Link Between Psoriasis and Crohn’s: Essential Insights for Clinical Practice Introduction Psoriasis and Crohn’s disease share a complex and clinically notable relationship that extends well beyond coincidental comorbidity. Psoriasis, a chronic immune-mediated skin condition, affects an estimated 2% to 3% of the global population,
Food Allergy Immunotherapy: Why Personalized Treatment Fails for Some Patients
Food Allergy Immunotherapy: Why Personalized Treatment Fails for Some Patients Introduction Food allergies affect 4–8% of children and 3–4% of adults worldwide, with immunotherapy allergy treatments emerging as promising interventions for this growing health burden. Even though allergy immunotherapy was first used in
