Lithium Effects On Renal Function In Geriatric Patients Overview The practice of augmenting antidepressant therapy with lithium, known as Lithium Augmentation (LA), is considered a primary treatment option for individuals suffering from Treatment-Resistant Depression (TRD). However, in the case of geriatric patients, this approach is notably underutilized due to concerns surrounding potential
Family Practice Medicine
Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease
Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease The Study The study aimed to investigate the connection between localized vascular and retinal nerve fiber layer (RNFL) loss and an individual's genetic predisposition to both glaucoma and cardiovascular disease. Researchers used a statistical tool called polygenic risk scores (PRS) to assess
Azelaic Acid Treatment For Rosacea and Melasma
Azelaic Acid Treatment For Rosacea and Melasma Overview This study evaluated the effectiveness and safety of topical azelaic acid (AA) for various dermatological conditions, including acne vulgaris, rosacea, hyperpigmentation/melasma, and skin aging. The researchers conducted a systematic review of randomized controlled trials (RCTs) with a minimum treatment duration of 6 weeks, searching
Rheumatoid Arthritis Work Limitation Factors
Rheumatoid Arthritis Work Limitation Factors Rheumatic and musculoskeletal diseases (RMD) introduce pain and functional limitations into the workplace, affecting individuals with rheumatoid arthritis and osteoarthritis. This study delves into the multifaceted factors that shape the work challenges arising from RMD, acknowledging the broader societal costs involved. By shedding light on these
Necrotizing Fasciitis Treatment And Bacterial Isolates Mortality Risk
Necrotizing Fasciitis Treatment And Bacterial Isolates Mortality Risk Necrotizing fasciitis, although rare, is a highly concerning and progressive medical condition. Its rarity doesn't diminish its potential to become life-threatening due to the systemic toxicity it can unleash on the body. This condition is primarily characterized by a fast-spreading infection within the
Acellular Dermal Matrix (ADM) For Burn and Trauma Wounds
Acellular Dermal Matrix (ADM) For Burn and Trauma Wounds In full-thickness skin defects, involving the epidermis, dermis, and subcutaneous tissue, skin grafting is a common method for repair. Traditional grafting involves cutting the patient's own skin for transplantation, with variations like ultra-thin split-thickness, medium-thickness, and full-thickness grafts depending on skin thickness
Perforator Flaps For Patellar Defects
Perforator Flaps For Patellar Defects Overview This study explores the use of pedicled fascio-cutaneous perforator flaps, specifically the descending genicular artery perforator (DGAP) flap, for reconstructing complex peripatellar defects. While free flaps and pedicled muscle flaps are more commonly employed for this purpose, the DGAP flap is presented as a viable and
GERD And Risk Factors Of Age And Obesity
GERD And Risk Factors Of Age And Obesity Overview In this study, the researchers sought to investigate the diagnostic value of nocturnal baseline impedance (MNBI) in identifying gastroesophageal reflux disease (GERD) while considering the potential influence of age and body mass index (BMI) on MNBI levels. The study involved a cohort of 311
AKI In Alcohol-Related Hepatitis
AKI In Alcohol-Related Hepatitis The prevalence, prediction, and impact of acute kidney injury (AKI) in alcohol-related hepatitis (AH) remain uncertain. AH is the most severe form of alcohol-related liver disease (ARLD) with a 30% mortality rate within 90 days, often aggravated by AKI, either as a primary or secondary cause. Research suggests
Biologic Therapy Tapering In Inflammatory Arthritis
Biologic Therapy Tapering In Inflammatory Arthritis Overview The aim of this study was to identify predictors of successful biologic tapering in patients with inflammatory arthritis, using baseline characteristics from the BIODOPT trial. The trial included adult patients with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who had been on a stable biologic
